SCHEMBL906834

SCHEMBL906834

CC(C)(C)[Si](C)(C)OCc1ccc(O)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.48
ESR1 P03372 9/20 0.47
BACE1 P56817 1/20 0.44
ESR2 Q92731 7/20 0.42
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
BLM P54132 1/20 0.38
ABAT P80404 1/20 0.37
LMNA P02545 1/20 0.37
TYR P14679 1/20 0.37
CYP3A4 P08684 1/20 0.37
AR P10275 1/20 0.37
HPGD P15428 1/20 0.37
TSHR P16473 1/20 0.37
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
HTR6 P50406 1/20 0.37
ESRRG P62508 1/20 0.37
SLC6A3 Q01959 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3178345 0.86 PPARG (0.40) IDO1ESR1BACE1MEN1KMT2A
SCHEMBL12855670 0.84 AGXT (0.52) IDO1TSHR
SCHEMBL15489965 0.84 TDP1 (0.37) BACE1KMT2A
SCHEMBL31138172 0.83 BACE1 (0.36) IDO1ESR1BACE1
SCHEMBL2876790 0.83 CA2 (0.45) BACE1TSHR
SCHEMBL2821530 0.83 ESR1 (0.45) IDO1ESR1BACE1ESR2MEN1
SCHEMBL3426875 0.82 AGXT (0.32) IDO1BACE1CYP3A4
SCHEMBL18954528 0.82 MAOB (0.41) IDO1ABAT
SCHEMBL7262934 0.82 AGXT (0.32) IDO1BACE1
SCHEMBL133816 0.82 MAOB (0.39) IDO1CYP3A4HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260102373-A1 LYMPH DIRECTING PRODRUGS MONASH UNIVERSITY (AU) 2026-04-16 US disclosed
US-12594339-B2 Lipid prodrugs of JAK inhibitors and uses thereof SEAPORT THERAPEUTICS, INC. (US) 2026-04-07 US disclosed
US-20260041661-A1 THREE-COMPONENT PRODRUG, PHARMACEUTICAL COMPOSITION THEREOF, AND MEDICAL USE THEREOF J2H BIOTECH INC. (KR) 2026-02-12 US disclosed
EP-4676535-A1 MULTI-ALBUMIN BINDING COMPOUNDS Ascendis Pharma A/S (DK) 2026-01-14 EP disclosed
US-20250352510-A1 LYMPH DIRECTING PRODRUGS MONASH UNIVERSITY (AU) 2025-11-20 US disclosed
US-20250213522-A1 LYMPH DIRECTING PRODRUGS MONASH UNIVERSITY (AU) 2025-07-03 US disclosed
EP-4578865-A2 LYMPH DIRECTING PRODRUGS Monash University (AU) 2025-07-02 EP disclosed
EP-3180349-B1 LYMPH DIRECTING PRODRUGS AND THERAPEUTIC USES THEREOF UNIV MONASH (AU) 2025-03-12 EP disclosed
US-20250041306-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM EUBULUS BIOTHERAPEUTICS INC. (CN) 2025-02-06 US disclosed
CN-119306780-A Lipid prodrugs of pregnane neurosteroids and uses thereof 海港治疗公司 2025-01-14 CN disclosed
EP-1362053-A4 TERMINALLY-BRANCHED POLYMERIC LINKERS AND POLYMERIC CONJUGATES CONTAINING THE SAME ENZON INC (US) 2005-01-19 EP disclosed
WO-2004012735-A2 NEW EFFECTOR CONJUGATES, PROCESS FOR THEIR PRODUCTION AND THEIR PHARMACEUTICAL USE SCHERING AG (DE) 2004-02-12 WO disclosed
EP-1362053-A2 TERMINALLY-BRANCHED POLYMERIC LINKERS AND POLYMERIC CONJUGATES CONTAINING THE SAME ENZON, INC. (US) 2003-11-19 EP disclosed
WO-2002065988-A2 TERMINALLY-BRANCHED POLYMERIC LINKERS AND POLYMERIC CONJUGATES CONTAINING THE SAME ENZON, INC. (US) 2002-08-29 WO disclosed
EP-0594588-A1 CYCLOALKYL-SUBSTITUTED GLUTARAMIDE ANTIHYPERTENSIVE AGENTS Pfizer Limited (GB) 1994-05-04 EP disclosed
US-5231113-A Skin disorders, immunology or wound healing agents ALLERGAN, INC. (US) 1993-07-27 US disclosed
EP-0337689-B1 TETRALIN ESTERS OF PHENOLS OR BENZOIC ACIDS HAVING RETINOID LIKE ACTIVITY ALLERGAN, INC (US) 1993-03-10 EP disclosed
US-5130335-A Treatment of skin disorders ALLERGAN, INC. (US) 1992-07-14 US disclosed
WO-1991013054-A1 CYCLOALKYL-SUBSTITUTED GLUTARAMIDE ANTIHYPERTENSIVE AGENTS PFIZER LIMITED (GB) 1991-09-05 WO disclosed
EP-0337689-A1 Tetralin esters of phenols or benzoic acids having retinoid like activity ALLERGAN, INC (US) 1989-10-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250041306-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM ADAMTS1, UCHL3, ADAM33 IDO1 1451/4885ESR1 1044/4885BACE1 100/4885
US-20260041661-A1 THREE-COMPONENT PRODRUG, PHARMACEUTICAL COMPOSITION THEREOF, AND MEDICAL USE THEREOF FPGS, TFB2M, UFM1 IDO1 1752/4885ESR1 4143/4885BACE1 55/4885
US-20260102373-A1 LYMPH DIRECTING PRODRUGS MALT1, CES1, LIPA IDO1 1549/4885ESR1 2160/4885BACE1 2310/4885
US-12594339-B2 Lipid prodrugs of JAK inhibitors and uses thereof JAK1, JAK3, JAK2 IDO1 223/4885ESR1 3181/4885BACE1 4312/4885
US-20250213522-A1 LYMPH DIRECTING PRODRUGS LTA, ABCB11, LYN IDO1 2252/4885ESR1 1606/4885BACE1 3195/4885
US-20250352510-A1 LYMPH DIRECTING PRODRUGS LTA, ABCB11, LYN IDO1 2252/4885ESR1 1606/4885BACE1 3195/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.