SCHEMBL14801668

SCHEMBL14801668

Nc1c(C(=O)O)cccc1C(=O)/C=C/c1ccc(O)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.60
CYP3A4 P08684 6/20 0.60
KMT2A Q03164 5/20 0.60
MEN1 O00255 4/20 0.60
TDP1 Q9NUW8 4/20 0.60
HPGD P15428 3/20 0.60
ALOX15 P16050 3/20 0.60
MAPK1 P28482 3/20 0.60
TP53 P04637 2/20 0.60
MAOA P21397 2/20 0.60
MAOB P27338 2/20 0.60
KDM4E B2RXH2 2/20 0.60
ALDH1A1 P00352 2/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
ALOX12 P18054 1/20 0.60
NFKB1 P19838 3/20 0.55
PKM P14618 3/20 0.55
NFKB2 Q00653 2/20 0.55
RELA Q04206 2/20 0.55
HSPD1 P10809 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14801670 1.00 MAPT (0.60) MAPTCYP3A4KMT2AMEN1TDP1
SCHEMBL2843086 0.89 MAPT (0.73) MAPTCYP3A4KMT2AMEN1TDP1
SCHEMBL2843080 0.89 MAPT (0.73) MAPTCYP3A4KMT2AMEN1TDP1
SCHEMBL14801690 0.84 MAPT (0.65) MAPTCYP3A4KMT2AMEN1TDP1
SCHEMBL25190924 0.84 MAPT (0.73) MAPTCYP3A4KMT2AMEN1TDP1
SCHEMBL25190631 0.83 MAPT (0.78) MAPTCYP3A4KMT2AMEN1TDP1
SCHEMBL25225496 0.83 MAPT (0.78) MAPTCYP3A4KMT2AMEN1TDP1
SCHEMBL14801792 0.79 MAPT (0.62) MAPTCYP3A4KMT2AMEN1TDP1
SCHEMBL14801794 0.79 MAPT (0.62) MAPTCYP3A4KMT2AMEN1TDP1
SCHEMBL3363562 0.78 PLA2G1B (0.60) MAPTTDP1HPGDKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10280441-B2 Host cells and methods for producing cinnamoyl anthranilate and analogs thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-05-07 US disclosed
US-20130078683-A1 Host Cells and Methods for Producing Cinnamoyl Anthranilate and Analogs Thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-03-28 US disclosed