SCHEMBL14801690

SCHEMBL14801690

Nc1c(C(=O)O)cccc1C(=O)C=Cc1ccc(O)c(O)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.65
KMT2A Q03164 3/20 0.65
KDM4E B2RXH2 3/20 0.65
PTGS1 P23219 2/20 0.65
PTGS2 P35354 2/20 0.65
GAA P10253 2/20 0.65
MAPK1 P28482 2/20 0.65
NPSR1 Q6W5P4 1/20 0.65
MYOC Q99972 1/20 0.65
TERT O14746 2/20 0.57
MEN1 O00255 2/20 0.56
AKR1B1 P15121 2/20 0.56
NFKB1 P19838 2/20 0.56
HDAC6 Q9UBN7 2/20 0.56
SNCA P37840 2/20 0.56
EGFR P00533 1/20 0.56
SRC P12931 1/20 0.56
CDK2 P24941 1/20 0.56
HSD17B2 P37059 1/20 0.56
PIK3CA P42336 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14802035 0.87 KMT2A (0.61) MAPTKMT2AKDM4EPTGS1PTGS2
SCHEMBL14801709 0.86 TERT (0.69) MAPTKMT2AKDM4EPTGS1PTGS2
SCHEMBL30382983 0.85 MAPT (0.77) MAPTKMT2AKDM4EPTGS1PTGS2
SCHEMBL8847553 0.85 MAPT (0.77) MAPTKMT2AKDM4EPTGS1PTGS2
SCHEMBL8847550 0.85 MAPT (0.77) MAPTKMT2AKDM4EPTGS1PTGS2
SCHEMBL14801790 0.85 PTGS1 (0.70) KMT2AKDM4EPTGS1PTGS2MEN1
SCHEMBL25200543 0.84 MAPT (0.75) MAPTKMT2AKDM4EPTGS1PTGS2
SCHEMBL14801670 0.84 MAPT (0.60) MAPTKMT2AKDM4EMAPK1NPSR1
SCHEMBL14801668 0.84 MAPT (0.60) MAPTKMT2AKDM4EMAPK1NPSR1
SCHEMBL2843080 0.82 MAPT (0.73) MAPTKMT2AKDM4EMAPK1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10280441-B2 Host cells and methods for producing cinnamoyl anthranilate and analogs thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-05-07 US disclosed
US-20130078683-A1 Host Cells and Methods for Producing Cinnamoyl Anthranilate and Analogs Thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-03-28 US disclosed