SCHEMBL14801992

SCHEMBL14801992

COc1cc(C=CC(=O)Nc2c(O)cccc2C(=O)O)cc(OC)c1OC

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.60
KDM4E B2RXH2 7/20 0.60
HPGD P15428 7/20 0.60
LMNA P02545 3/20 0.60
NPSR1 Q6W5P4 2/20 0.60
GAA P10253 2/20 0.60
MAPT P10636 3/20 0.60
LTB4R Q15722 1/20 0.59
HTT P42858 2/20 0.56
SMN1; SMN2 Q16637 3/20 0.55
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
CYP3A4 P08684 3/20 0.55
TP53 P04637 2/20 0.55
HIF1A Q16665 2/20 0.55
CYP1A2 P05177 2/20 0.55
CYP2C19 P33261 2/20 0.55
HSD17B10 Q99714 2/20 0.55
CA12 O43570 1/20 0.55
CA1 P00915 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8636613 0.90 ALDH1A1 (0.59) ALDH1A1KDM4EHPGDLMNANPSR1
SCHEMBL8636635 0.90 ALDH1A1 (0.59) ALDH1A1KDM4EHPGDLMNANPSR1
SCHEMBL14802041 0.89 MEN1 (0.70) ALDH1A1KDM4EHPGDNPSR1GAA
SCHEMBL14801680 0.89 KDM1A (0.67) ALDH1A1KDM4EHPGDLMNANPSR1
SCHEMBL20537712 0.85 HTT (0.57) ALDH1A1KDM4EHPGDLMNANPSR1
SCHEMBL20537714 0.85 HTT (0.57) ALDH1A1KDM4EHPGDLMNANPSR1
SCHEMBL14801947 0.84 TRPM8 (0.58) MAPTLTB4RSMN1; SMN2MEN1KMT2A
SCHEMBL20537770 0.84 ALDH1A1 (0.54) ALDH1A1KDM4EHPGDLMNANPSR1
SCHEMBL20537771 0.84 ALDH1A1 (0.54) ALDH1A1KDM4EHPGDLMNANPSR1
SCHEMBL20537772 0.84 ALDH1A1 (0.54) ALDH1A1KDM4EHPGDLMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10280441-B2 Host cells and methods for producing cinnamoyl anthranilate and analogs thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-05-07 US disclosed
US-20130078683-A1 Host Cells and Methods for Producing Cinnamoyl Anthranilate and Analogs Thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-03-28 US disclosed