Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5448696 | 0.91 | PRKDC (0.61) | PRKDC | |
| SCHEMBL5453460 | 0.89 | PRKDC (0.63) | PRKDCPOLB | |
| SCHEMBL5440522 | 0.88 | PRKDC (0.48) | PRKDCPOLB | |
| SCHEMBL5454450 | 0.88 | PRKDC (0.48) | PRKDCPOLB | |
| SCHEMBL5456163 | 0.87 | P2RY12 (0.63) | PRKDC | |
| SCHEMBL5454078 | 0.87 | PRKDC (0.50) | PRKDCPOLB | |
| SCHEMBL14802146 | 0.86 | PRKDC (0.47) | PRKDCPOLB | |
| SCHEMBL5446334 | 0.85 | PRKDC (0.51) | PRKDC | |
| SCHEMBL14802156 | 0.85 | PRKDC (0.59) | PRKDC | |
| SCHEMBL14802144 | 0.84 | ALDH1A1 (0.47) | PRKDCPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404681-B2 | Xanthones, thioxanthones and acridinones as DNA-PK inhibitors | LUITPOLD PHARMACEUTICALS, INC. (US) | 2013-03-26 | — | — | US | disclosed |