SCHEMBL14804313

SCHEMBL14804313

Brc1ccc(C2(c3ccc(Br)cc3)CCC(c3ccccc3)(c3ccccc3)CC2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 7/20 0.52
MEN1 O00255 1/20 0.50
CYP2C9 P11712 1/20 0.50
KMT2A Q03164 1/20 0.50
ALDH1A1 P00352 3/20 0.46
TDP1 Q9NUW8 1/20 0.46
MAPK1 P28482 2/20 0.44
GRIN2D O15399 1/20 0.44
GRIN3B O60391 1/20 0.44
CHRM2 P08172 1/20 0.44
CHRM1 P11229 1/20 0.44
GRIN1 Q05586 1/20 0.44
KCNH2 Q12809 1/20 0.44
GRIN2A Q12879 1/20 0.44
GRIN2B Q13224 1/20 0.44
GRIN2C Q14957 1/20 0.44
GRIN3A Q8TCU5 1/20 0.44
CYP2D6 P10635 1/20 0.44
HTR2A P28223 1/20 0.43
KDM1A O60341 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14804316 1.00 OPRM1 (0.52) OPRM1MEN1CYP2C9KMT2AALDH1A1
SCHEMBL23198889 1.00 OPRM1 (0.52) OPRM1MEN1CYP2C9KMT2AALDH1A1
SCHEMBL28271182 0.90 CYP2A6 (0.47) OPRM1MEN1CYP2C9KMT2AALDH1A1
SCHEMBL2256575 0.84 OPRM1 (0.67) OPRM1MEN1CYP2C9KMT2AGRIN2D
SCHEMBL2256573 0.84 OPRM1 (0.67) OPRM1MEN1CYP2C9KMT2AGRIN2D
Bromide SCHEMBL28969840 0.82 OPRM1 (0.64) OPRM1MEN1CYP2C9KMT2AGRIN2D
Ammonia Solution, Strong SCHEMBL1158702 0.82 OPRM1 (0.64) OPRM1MEN1CYP2C9KMT2AGRIN2D
SCHEMBL14804303 0.81 PDK2 (0.38) OPRM1MEN1CYP2C9KMT2ATDP1
SCHEMBL19830974 0.81 PNMT (0.58) OPRM1ALDH1A1TDP1MAPK1KDM1A
SCHEMBL14804302 0.80 MEN1 (0.45) OPRM1MEN1CYP2C9KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130075714-A1 POLYMER, POLYMER COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE SUMTOMO CHEMICAL COMPANY LIMITED (JP) 2013-03-28 US disclosed
US-20130075714-A1 POLYMER, POLYMER COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE SUMTOMO CHEMICAL COMPANY LIMITED (JP) 2013-03-28 US disclosed