SCHEMBL14804339

SCHEMBL14804339

CC1(C)OB(c2ccc(C34CC5CC(C3)CC(c3ccc(B6OC(C)(C)C(C)(C)O6)cc3)(C5)C4)cc2)OC1(C)C

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.45
LPL P06858 7/20 0.44
LIPG Q9Y5X9 7/20 0.44
PGR P06401 4/20 0.42
ALDH1A1 P00352 3/20 0.42
GRIN2D O15399 1/20 0.41
GRIN3B O60391 1/20 0.41
GRIN1 Q05586 1/20 0.41
GRIN2A Q12879 1/20 0.41
GRIN2B Q13224 1/20 0.41
GRIN2C Q14957 1/20 0.41
GRIN3A Q8TCU5 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
LMNA P02545 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
ESR1 P03372 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16384880 0.90 HIF1A (0.52) HIF1ALPLLIPGALDH1A1NPC1
SCHEMBL23627776 0.85 HIF1A (0.38) HIF1ALPLLIPGALDH1A1NPC1
SCHEMBL21021720 0.85 LPL (0.53) LPLLIPG
SCHEMBL19831188 0.85 LPL (0.53) LPLLIPG
SCHEMBL16519666 0.83 HIF1A (0.48) HIF1APGRLMNAMEN1KMT2A
SCHEMBL2257810 0.83 HIF1A (0.48) HIF1APGRLMNAMEN1KMT2A
SCHEMBL14804340 0.82 LPL (0.41) HIF1ALPLLIPGPGRALDH1A1
SCHEMBL25709668 0.80 HIF1A (0.45) HIF1ALPLLIPGALDH1A1NPC1
SCHEMBL25709721 0.80 HIF1A (0.45) HIF1ALPLLIPGALDH1A1NPC1
SCHEMBL2255114 0.80 HIF1A (0.48) HIF1APGRALDH1A1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021135517-A1 ORGANIC COMPOUND, ELECTRONIC COMPONENT AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2021-07-08 WO disclosed
US-20130075714-A1 POLYMER, POLYMER COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE SUMTOMO CHEMICAL COMPANY LIMITED (JP) 2013-03-28 US disclosed
US-20130075714-A1 POLYMER, POLYMER COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE SUMTOMO CHEMICAL COMPANY LIMITED (JP) 2013-03-28 US disclosed