SCHEMBL14804340

SCHEMBL14804340

CC1(C)OB(c2cccc(C34CC5CC(C3)CC(c3cccc(B6OC(C)(C)C(C)(C)O6)c3)(C5)C4)c2)OC1(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPL P06858 7/20 0.41
LIPG Q9Y5X9 7/20 0.41
HIF1A Q16665 1/20 0.40
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
GRIN1 Q05586 1/20 0.40
GRIN2A Q12879 1/20 0.40
GRIN2B Q13224 1/20 0.40
GRIN2C Q14957 1/20 0.40
GRIN3A Q8TCU5 1/20 0.40
PGR P06401 2/20 0.33
ALDH1A1 P00352 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
RAD52 P43351 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
GFER P55789 1/20 0.33
IRAK4 Q9NWZ3 1/20 0.32
HSD11B1 P28845 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20853361 0.92 HIF1A (0.46) LPLLIPGHIF1AGRIN2DGRIN3B
SCHEMBL14804339 0.82 HIF1A (0.45) LPLLIPGHIF1AGRIN2DGRIN3B
SCHEMBL31074756 0.76 HTT (0.44) LPLLIPGHIF1AALDH1A1MEN1
SCHEMBL16384880 0.73 HIF1A (0.52) LPLLIPGHIF1AALDH1A1MEN1
SCHEMBL1476213 0.73 LIPG (0.59) LPLLIPGIRAK4
SCHEMBL14804291 0.72 GRIN2D (0.49) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL24175626 0.72 LIPG (0.46) LPLLIPGIRAK4
SCHEMBL28843389 0.72 LIPG (0.46) LPLLIPGIRAK4
SCHEMBL29933385 0.72 LIPG (0.46) LPLLIPGIRAK4
SCHEMBL30404611 0.72 LIPG (0.46) LPLLIPGIRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130075714-A1 POLYMER, POLYMER COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE SUMTOMO CHEMICAL COMPANY LIMITED (JP) 2013-03-28 US disclosed
US-20130075714-A1 POLYMER, POLYMER COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE SUMTOMO CHEMICAL COMPANY LIMITED (JP) 2013-03-28 US disclosed