Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | LGMN | Q99538 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 9/20 | 0.37 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17938310 | 0.90 | KCNH2 (0.39) | KCNH2MAP4K4PIK3CAMINK1PI4KB | |
| SCHEMBL688462 | 0.89 | KCNH2 (0.39) | KCNH2MAP4K4PIK3CAMINK1PI4KB | |
| SCHEMBL1480997 | 0.89 | KCNH2 (0.39) | KCNH2MAP4K4PIK3CAMINK1PI4KB | |
| SCHEMBL1480223 | 0.88 | KCNH2 (0.38) | KCNH2MAP4K4PIK3CAMINK1PI4KB | |
| SCHEMBL12464357 | 0.88 | KCNH2 (0.41) | KCNH2MAP4K4PIK3CAMINK1PI4KB | |
| SCHEMBL10139144 | 0.88 | KCNH2 (0.39) | KCNH2MAP4K4PIK3CAMINK1PI4KB | |
| SCHEMBL1480174 | 0.88 | KCNH2 (0.39) | KCNH2MAP4K4PIK3CAMINK1PI4KB | |
| SCHEMBL1481057 | 0.87 | KCNH2 (0.38) | KCNH2MAP4K4PIK3CAMINK1PI4KB | |
| SCHEMBL1482621 | 0.86 | KCNH2 (0.37) | KCNH2MAP4K4PIK3CAMINK1PI4KB | |
| SCHEMBL17938309 | 0.85 | P2RX7 (0.38) | KCNH2MAP4K4PIK3CAMINK1PI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268615-B1 | PESTICIDES | DOW AGROSCIENCES LLC (US) | 2016-08-17 | — | — | EP | disclosed |
| EP-2268615-B1 | PESTICIDES | DOW AGROSCIENCES LLC (US) | 2016-08-17 | — | — | EP | disclosed |
| US-8445689-B2 | Pesticides | DOW AGROSCIENCES, LLC. (US) | 2013-05-21 | — | — | US | disclosed |
| US-8445689-B2 | Pesticides | DOW AGROSCIENCES, LLC. (US) | 2013-05-21 | — | — | US | disclosed |
| US-20120225782-A1 | PESTICIDES | DOW AGROSCIENCES LLC (US) | 2012-09-06 | — | — | US | disclosed |
| US-20120225782-A1 | PESTICIDES | DOW AGROSCIENCES LLC (US) | 2012-09-06 | — | — | US | disclosed |
| US-8178685-B2 | Pesticides | DOW AGROSCIENCES, LLC (US) | 2012-05-15 | — | — | US | disclosed |
| US-8178685-B2 | Pesticides | DOW AGROSCIENCES, LLC (US) | 2012-05-15 | — | — | US | disclosed |
| US-20110077160-A1 | PESTICIDES | DOW AGROSCIENCES LLC | 2011-03-31 | — | — | US | disclosed |
| US-20110077160-A1 | PESTICIDES | DOW AGROSCIENCES LLC | 2011-03-31 | — | — | US | disclosed |
| WO-2009111309-A1 | PESTICIDES | DOW AGROSCIENCES LLC (US) | 2009-09-11 | — | — | WO | disclosed |
| US-20090221424-A1 | PESTICIDES | DOW AGROSCIENCES LLC (US) | 2009-09-03 | — | — | US | disclosed |
| US-20090221424-A1 | PESTICIDES | DOW AGROSCIENCES LLC (US) | 2009-09-03 | — | — | US | disclosed |
| US-20090221424-A1 | PESTICIDES | DOW AGROSCIENCES LLC (US) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120225782-A1 | PESTICIDES | ACHE, DDT, GSTP1 | KCNH2 122/4885MAP4K4 4608/4885PIK3CA 1609/4885 |
| US-20090221424-A1 | PESTICIDES | ACHE, DDT, GSTP1 | KCNH2 121/4885MAP4K4 4610/4885PIK3CA 1617/4885 |
| US-20110077160-A1 | PESTICIDES | ACHE, DDT, GSTP1 | KCNH2 121/4885MAP4K4 4610/4885PIK3CA 1617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.