SCHEMBL14810474

SCHEMBL14810474

O=C1C=NC2=C1CCC=C2

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10933855 0.64
SCHEMBL19336228 0.64 ALDH1A1 (0.42) ALDH1A1
SCHEMBL15160718 0.61 TRPA1 (0.40) ALDH1A1
SCHEMBL296267 0.59
SCHEMBL20897220 0.59 TRPA1 (0.39) ALDH1A1
SCHEMBL693032 0.58 ALDH1A1 (0.68) ALDH1A1
SCHEMBL24628 0.58
SCHEMBL6625847 0.58
SCHEMBL2505370 0.58
SCHEMBL18932499 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2758392-A1 USE OF STRIGOLACTONES AND STRIGOLACTONE ANALOGS FOR TREATING PROLIFERATIVE CONDITIONS The State of Israel - Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Center) (IL) 2014-07-30 EP disclosed
WO-2013042124-A1 USE OF STRIGOLACTONES AND STRIGOLACTONE ANALOGS FOR TREATING PROLIFERATIVE CONDITIONS THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) 2013-03-28 WO disclosed