SCHEMBL14813331

SCHEMBL14813331

CC/C=C/C(=O)NCC[O]

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
CNR1 P21554 5/20 0.35
CNR2 P34972 3/20 0.35
ZDHHC20 Q5W0Z9 3/20 0.34
ZDHHC2 Q9UIJ5 2/20 0.34
EGFR P00533 1/20 0.33
LMNA P02545 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TAS1R3 Q7RTX0 1/20 0.32
TAS1R1 Q7RTX1 1/20 0.32
TRPA1 O75762 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
APP P05067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14813332 1.00 ALDH1A1 (0.37) ALDH1A1CNR1CNR2ZDHHC20ZDHHC2
SCHEMBL11296642 0.84 ALDH1A1 (0.45) ALDH1A1CNR1CNR2ZDHHC20ZDHHC2
SCHEMBL22109092 0.83 CNR1 (0.49) ALDH1A1CNR1CNR2MAPTKMT2A
SCHEMBL14813333 0.83 CNR1 (0.49) ALDH1A1CNR1CNR2MAPTKMT2A
SCHEMBL9111857 0.81 ZDHHC20 (0.50) ALDH1A1CNR1CNR2ZDHHC20ZDHHC2
SCHEMBL19261723 0.81 ZDHHC20 (0.50) ALDH1A1CNR1CNR2ZDHHC20ZDHHC2
SCHEMBL27989479 0.81 ZDHHC20 (0.37) ALDH1A1CNR1CNR2ZDHHC20ZDHHC2
SCHEMBL13123961 0.79
SCHEMBL28708124 0.79
SCHEMBL12127403 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1951686-B1 QUINAZOLINE DERIVATIVES AS A MULTIPLEX INHIBITOR AND METHOD FOR THE PREPARATION THEREOF HANMI PHARM IND CO LTD (KR) 2013-04-03 EP claimed