Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4461877 | 0.77 | SLC6A2 (0.48) | CYP2D6CYP2C19SLC6A2SLC6A4CHRM2 | |
| SCHEMBL7594235 | 0.75 | KDM4E (0.42) | SLC6A2SLC6A4HTR2AHRH1KDM4E | |
| SCHEMBL2132415 | 0.73 | CHRM2 (0.49) | CYP2D6CYP2C19SLC6A2SLC6A4CHRM2 | |
| SCHEMBL11701437 | 0.73 | CYP2D6 (0.63) | CYP2D6CYP2C19SLC6A2SLC6A4CHRM2 | |
| SCHEMBL19306196 | 0.71 | TSHR (0.62) | CYP2C19KDM4ETSHRLMNAMAPK1 | |
| SCHEMBL11697719 | 0.71 | CYP2D6 (0.51) | CYP2D6CYP2C19SLC6A2SLC6A4CHRM2 | |
| SCHEMBL31490354 | 0.70 | POLB (0.58) | CYP2D6CYP2C19SLC6A2SLC6A4CHRM2 | |
| SCHEMBL440638 | 0.70 | POLB (0.58) | CYP2D6CYP2C19SLC6A2SLC6A4CHRM2 | |
| Ethylene SCHEMBL28037648 | 0.70 | CHRM2 (0.46) | CYP2D6CYP2C19SLC6A2SLC6A4CHRM2 | |
| SCHEMBL2495689 | 0.70 | SLC6A2 (0.42) | CYP2D6CYP2C19SLC6A2SLC6A4CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2580198-B1 | THERMOLABILE 2-(N-2-PYRIDIYL-N-BENZYL)-AMINOETHYLOXYCARBONYL DERIVATIVES AS HYDROXYL FUNCTION PROTECTING AGENTS | INST CHEMII BIOORG POLSKIEJ AKADEMII NAUK (PL) | 2016-08-10 | — | — | EP | disclosed |
| US-8759509-B2 | Way of using thermolabile groups to protect hydroxyl functions and compounds for implementing the procedure | INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK (PL) | 2014-06-24 | — | — | US | disclosed |
| EP-2580198-A1 | THERMOLABILE 2 - (N- 2 - PYRIDIYL - N- BENZYL) - AMINOETHYLOXYCARBONYL DERIVATIVES AS HYDROXYL FUNCTION PROTECTING AGENTS | Instytut Chemii Bioorganicznej Polskiej Akademii Nauk (PL) | 2013-04-17 | — | — | EP | disclosed |
| US-20130085272-A1 | NEW WAY OF USING THERMOLABILE GROUPS TO PROTECT HYDROXYL FUNCTIONS, AND NEW COMPOUNDS FOR IMPLEMENTING THE PROCEDURE | INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK (PL) | 2013-04-04 | — | — | US | disclosed |
| US-20130085272-A1 | NEW WAY OF USING THERMOLABILE GROUPS TO PROTECT HYDROXYL FUNCTIONS, AND NEW COMPOUNDS FOR IMPLEMENTING THE PROCEDURE | INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK (PL) | 2013-04-04 | — | — | US | disclosed |
| WO-2011155855-A1 | THERMOLABILE 2 - (N- 2 - PYRIDIYL - N- BENZYL) - AMINOETHYLOXYCARBONYL DERIVATIVES AS HYDROXYL FUNCTION PROTECTING AGENTS | INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK (PL) | 2011-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130085272-A1 | NEW WAY OF USING THERMOLABILE GROUPS TO PROTECT HYDROXYL FUNCTIONS, AND NEW COMPOUNDS FOR IMPLEMENTING THE PROCEDURE | RNGTT, POLB, UNG | CYP2D6 1150/4885CYP2C19 1030/4885SLC6A2 2900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.