SCHEMBL2495689

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2495631	0.92	SLC6A2 (0.41)	SLC6A2SLC6A4LMNATRPM8AOC3
	SCHEMBL2492244	0.81	MEN1 (0.40)	LMNAAOC3HTR2AHRH1TRPA1
	SCHEMBL2490779	0.81	SLC6A2 (0.45)	SLC6A2SLC6A4LMNAMEN1KMT2A
	SCHEMBL7594235	0.78	KDM4E (0.42)	SLC6A2SLC6A4LMNAHTR2AHRH1
	SCHEMBL28434162	0.76	GAA (0.35)	SLC6A2SLC6A4LMNATRPM8CYP2D6
	SCHEMBL29421638	0.74	ALDH1A1 (0.47)	SLC6A2SLC6A4LMNATRPM8CYP3A4
	SCHEMBL94000	0.74	ALDH1A1 (0.47)	SLC6A2SLC6A4LMNATRPM8CYP3A4
	SCHEMBL2491891	0.73	MEN1 (0.39)	LMNAAOC3HTR2AHRH1MEN1
	SCHEMBL2492865	0.73	SLC6A2 (0.44)	SLC6A2SLC6A4LMNAMEN1KMT2A
	SCHEMBL11702654	0.72	ALDH1A1 (0.45)	SLC6A2SLC6A4LMNATRPM8CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.