SCHEMBL14816019

SCHEMBL14816019

C#CCCCCOP(=O)(O)OP(=O)(O)O.CCCCN(CCCC)CCCC.CCCCN(CCCC)CCCC.CCCCN(CCCC)CCCC

nearest known ligand 0.66

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ LPAR3 Q9UBY5 6/20 0.41
▸ LPAR1 Q92633 4/20 0.41
▸ LPAR2 Q9HBW0 3/20 0.41
▸ MVD P53602 2/20 0.40
▸ BTN3A1 O00481 1/20 0.38
▸ GGPS1 O95749 4/20 0.37
▸ FDPS P14324 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14816068 0.85 BTN3A1 (0.44) LPAR3LPAR1LPAR2MVDBTN3A1
Pent-4-Ynyl Diphosphate SCHEMBL1652909 0.81 BTN3A1 (0.46) LPAR3LPAR1LPAR2MVDBTN3A1
SCHEMBL8861514 0.78 MVD (0.41) LPAR3LPAR1LPAR2MVDBTN3A1
SCHEMBL2869539 0.77 LPAR3 (0.67) LPAR3LPAR1LPAR2MVDBTN3A1
Triphosphate SCHEMBL5052598 0.77 MMP1 (0.44) LPAR3LPAR1LPAR2MVDBTN3A1
Triphosphate SCHEMBL5052601 0.77 MMP1 (0.44) LPAR3LPAR1LPAR2MVDBTN3A1
SCHEMBL16417850 0.76 LPAR3 (0.47) LPAR3LPAR1LPAR2
SCHEMBL7850798 0.76 LPAR3 (0.70) LPAR3LPAR1LPAR2BTN3A1
SCHEMBL2858464 0.76 LPAR3 (0.70) LPAR3LPAR1LPAR2BTN3A1
SCHEMBL6820795 0.76 LPAR3 (0.70) LPAR3LPAR1LPAR2BTN3A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10378051-B2 Continuous extension and deblocking in reactions for nucleic acids synthesis and sequencing ILLUMINA CAMBRIDGE LIMITED (GB) 2019-08-13 — — US disclosed
EP-3293272-A1 CONTINUOUS EXTENSION AND DEBLOCKING IN REACTIONS FOR NUCLEIC ACID SYNTHESIS AND SEQUENCING Illumina, Inc. (US) 2018-03-14 — — EP disclosed
EP-2761026-A1 CONTINUOUS EXTENSION AND DEBLOCKING IN REACTIONS FOR NUCLEIC ACID SYNTHESIS AND SEQUENCING Illumina, Inc. (US) 2014-08-06 — — EP disclosed
WO-2013045939-A1 CONTINUOUS EXTENSION AND DEBLOCKING IN REACTIONS FOR NUCLEIC ACID SYNTHESIS AND SEQUENCING ILLUMINA, INC. (US) 2013-04-04 — — WO disclosed
US-20130085073-A1 CONTINUOUS EXTENSION AND DEBLOCKING IN REACTIONS FOR NUCLLEIC ACIDS SYNTHESIS AND SEQUENCING ILLUMINA CAMBRIDGE LIMITED (GB) 2013-04-04 — — US disclosed
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