Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 9/20 | 0.47 |
| ▸ | LPAR2 | Q9HBW0 | 8/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.47 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | P2RY10 | O00398 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.35 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26334850 | 0.91 | CYP2D6 (0.42) | LPAR3LPAR2LPAR1CYP1A2CYP2D6 | |
| SCHEMBL26334849 | 0.91 | CYP2D6 (0.42) | LPAR3LPAR2LPAR1CYP1A2CYP2D6 | |
| SCHEMBL26334858 | 0.91 | CYP2D6 (0.42) | LPAR3LPAR2LPAR1CYP1A2CYP2D6 | |
| SCHEMBL26334857 | 0.89 | CYP2D6 (0.39) | LPAR3LPAR2LPAR1CYP1A2CYP2D6 | |
| SCHEMBL22193586 | 0.88 | LPAR3 (0.40) | LPAR3LPAR2LPAR1CYP1A2CYP2D6 | |
| SCHEMBL25584062 | 0.84 | LPAR3 (0.40) | LPAR3LPAR2LPAR1CYP1A2CYP2D6 | |
| SCHEMBL17327639 | 0.82 | LPAR3 (0.37) | LPAR3LPAR2LPAR1CYP1A2CYP2D6 | |
| SCHEMBL26460406 | 0.82 | LPAR3 (0.36) | LPAR3LPAR2LPAR1CYP2D6P2RY10 | |
| SCHEMBL11994572 | 0.82 | LMNA (0.46) | LPAR3LPAR2LPAR1 | |
| SCHEMBL8738432 | 0.82 | LMNA (0.46) | LPAR3LPAR2LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940907-B2 | Synthesis of phosphoric esters | MERCK PATENT GMBH (DE) | 2015-01-27 | — | — | US | disclosed |