Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 4/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | ACR | P10323 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12787696 | 0.89 | MAPT (0.46) | PARP15PARP10PARP2DRD2DRD4 | |
| SCHEMBL12730859 | 0.88 | SIGMAR1 (0.45) | PARP15PARP10PARP2CYP1A2CYP2D6 | |
| SCHEMBL12730858 | 0.88 | LMNA (0.50) | PARP15PARP10PARP2PRSS1ACR | |
| SCHEMBL12730774 | 0.88 | PARP15 (0.44) | PARP15PARP10PARP2DRD2DRD4 | |
| SCHEMBL12730766 | 0.88 | PARP15 (0.44) | PARP15PARP10PARP2DRD2DRD4 | |
| SCHEMBL12730862 | 0.87 | PARP15 (0.43) | PARP15PARP10PARP2DRD2DRD4 | |
| SCHEMBL14817248 | 0.87 | PARP15 (0.43) | PARP15PARP10PARP2 | |
| SCHEMBL16172290 | 0.87 | PARP15 (0.41) | PARP15PARP10PARP2DRD2DRD4 | |
| SCHEMBL12730656 | 0.86 | MAPT (0.40) | PARP15PARP10PARP2PRSS1ACR | |
| SCHEMBL12730687 | 0.86 | LMNA (0.43) | PARP15PARP10PARP2PRSS1ACR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404316-B2 | Polymerizable liquid crystal compound and its polymer | JNC CORPORATION (JP) | 2013-03-26 | — | — | US | disclosed |