Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.53 |
| ▸ | ECE1 | P42892 | 1/20 | 0.51 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.47 |
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | GHSR | Q92847 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31181219 | 0.84 | GNPAT (0.57) | GNPATCPB2GHSR | |
| SCHEMBL29576990 | 0.83 | ECE1 (0.63) | ECE1CPB2CPB1ITGB3ITGA2B | |
| SCHEMBL17553670 | 0.82 | CTSL (0.47) | ECE1CPB2CTSLGHSR | |
| SCHEMBL31181203 | 0.82 | GNPAT (0.57) | GNPATECE1CPB2ITGB3ITGA2B | |
| SCHEMBL1711233 | 0.81 | GNPAT (0.62) | GNPATECE1CPB2GHSR | |
| SCHEMBL31254405 | 0.81 | GNPAT (0.62) | GNPATECE1CPB2GHSR | |
| SCHEMBL1711230 | 0.81 | GNPAT (0.62) | GNPATECE1CPB2GHSR | |
| SCHEMBL1711453 | 0.81 | GNPAT (0.62) | GNPATECE1CPB2GHSR | |
| SCHEMBL1711458 | 0.81 | GNPAT (0.62) | GNPATECE1CPB2GHSR | |
| SCHEMBL14015259 | 0.81 | FOLH1 (0.43) | GNPATCPB2CPB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404650-B2 | Methods of treating cancer with doxazolidine and prodrugs thereof | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2013-03-26 | — | — | US | disclosed |