Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | GHSR | Q92847 | 1/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.42 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.41 |
| ▸ | FURIN | P09958 | 1/20 | 0.41 |
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17553675 | 0.88 | REN (0.44) | CTSL | |
| SCHEMBL17553454 | 0.85 | PTPN1 (0.48) | CTSLGHSRERAP2ERAP1LNPEP | |
| SCHEMBL17553615 | 0.84 | ALDH1A1 (0.48) | CTSL | |
| SCHEMBL14817637 | 0.82 | GNPAT (0.53) | CTSLGHSRCPB2ECE1 | |
| SCHEMBL17553674 | 0.80 | ALDH1A1 (0.44) | CTSL | |
| SCHEMBL9417292 | 0.75 | REN (0.57) | CTSL | |
| SCHEMBL20173868 | 0.74 | CTSL (0.69) | CTSL | |
| SCHEMBL17725968 | 0.73 | GHSR (0.68) | CTSLGHSRERAP2ERAP1LNPEP | |
| SCHEMBL21318267 | 0.73 | CTSL (0.69) | CTSLGHSRCPB2ECE1 | |
| SCHEMBL4927118 | 0.73 | FURIN (0.60) | CTSLGHSRHRH1FURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016029324-A1 | AZASULFURYLPEPTIDE-BASED CD36 MODULATORS AND USES THEREOF | RSEM, LIMITED PARTNERSHIP (CA) | 2016-03-03 | — | — | WO | disclosed |