Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 11/20 | 0.33 |
| ▸ | ANTXR2 | P58335 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.32 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.32 |
| ▸ | FGF2 | P09038 | 1/20 | 0.32 |
| ▸ | MDK | P21741 | 1/20 | 0.32 |
| ▸ | HRAS | P01112 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19674472 | 1.00 | TNF (0.35) | TNFMEN1USP2POLBKMT2A | |
| SCHEMBL14817729 | 1.00 | TNF (0.35) | TNFMEN1USP2POLBKMT2A | |
| SCHEMBL15296523 | 1.00 | TNF (0.35) | TNFMEN1USP2POLBKMT2A | |
| SCHEMBL15171149 | 1.00 | TNF (0.35) | TNFMEN1USP2POLBKMT2A | |
| SCHEMBL15171214 | 1.00 | TNF (0.35) | TNFMEN1USP2POLBKMT2A | |
| SCHEMBL16623000 | 0.94 | TNF (0.34) | TNFMEN1USP2POLBKMT2A | |
| SCHEMBL19674487 | 0.94 | TNF (0.34) | TNFMEN1USP2POLBKMT2A | |
| SCHEMBL16623022 | 0.94 | TNF (0.34) | TNFMEN1USP2POLBKMT2A | |
| SCHEMBL19674482 | 0.94 | TNF (0.34) | TNFMEN1USP2POLBKMT2A | |
| SCHEMBL14900299 | 0.94 | LGALS3 (0.32) | TNFPAX8LGALS3PTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857411-B1 | METHOD FOR PREPARING FULLY PROTECTION HEPARIN PENTASACCHARIDE AND INTERMEDIATE THEREOF | ZHEJIANG HISUN PHARM CO LTD (CN) | 2017-12-06 | — | — | EP | disclosed |
| EP-2809678-B1 | AN EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM | RELIABLE BIOPHARMACEUTICAL CORP (US) | 2017-03-22 | — | — | EP | disclosed |
| US-9243018-B2 | Synthetic heparin pentasaccharides | DR. REDDY'S LABORATORIES, SA (CH) | 2016-01-26 | — | — | US | disclosed |
| US-8987430-B2 | Efficient and scalable process for the manufacture of fondaparinux sodium | RELIABLE BIOPHARMACEUTICAL CORPORATION (US) | 2015-03-24 | — | — | US | disclosed |
| US-20150005485-A1 | SYNTHETIC HEPARIN PENTASACCHARIDES | ALCHEMIA LIMITED (AU) | 2015-01-01 | — | — | US | disclosed |
| US-20130261291-A1 | EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM | RELIABLE BIOPHARMACEUTICAL CORPORATION (US) | 2013-10-03 | — | — | US | disclosed |
| WO-2013115817-A1 | AN EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM | RELIABLE BIOPHARMACEUTICAL CORPORATION (US) | 2013-08-08 | — | — | WO | disclosed |
| US-8404833-B2 | Synthetic heparin disaccharides | ALCHEMIA LIMITED (AU) | 2013-03-26 | — | — | US | disclosed |
| US-20120220759-A1 | SYNTHETIC HEPARIN DISACCHARIDES | ALCHEMIA LIMITED (AU) | 2012-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220759-A1 | SYNTHETIC HEPARIN DISACCHARIDES | HPSE, DDOST, STT3A | TNF 1459/4885MEN1 1458/4885USP2 1936/4885 |
| US-20150005485-A1 | SYNTHETIC HEPARIN PENTASACCHARIDES | HPSE, DDOST, STT3A | TNF 1297/4885MEN1 1486/4885USP2 2043/4885 |
| US-20130261291-A1 | EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM | F11, F10, F2 | TNF 2145/4885MEN1 1482/4885USP2 3339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.