Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 2/20 | 0.49 |
| ▸ | ARG2 | P78540 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | TACR2 | P21452 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2622478 | 0.86 | ARG1 (0.47) | ARG1ARG2TNNC1S1PR1SGPL1 | |
| SCHEMBL14145263 | 0.82 | ALOX5 (0.47) | ARG1ARG2ALDH1A1IGF1RALOX15 | |
| SCHEMBL13932736 | 0.79 | S1PR1 (0.66) | ALDH1A1TNNC1S1PR1SGPL1S1PR4 | |
| SCHEMBL3117439 | 0.78 | BLM (0.61) | ARG1ARG2BLMESR1KDM4E | |
| SCHEMBL10778604 | 0.78 | BLM (0.61) | ARG1ARG2BLMESR1KDM4E | |
| SCHEMBL3117431 | 0.78 | BLM (0.61) | ARG1ARG2BLMESR1KDM4E | |
| SCHEMBL13953044 | 0.78 | ALOX5 (0.48) | ALDH1A1 | |
| SCHEMBL2632241 | 0.76 | S1PR1 (0.61) | ALDH1A1LMNATP53CYP3A4TNNC1 | |
| SCHEMBL14499316 | 0.75 | GRM2 (0.50) | ARG1ARG2SLC6A3KDM4EALDH1A1 | |
| SCHEMBL22033166 | 0.74 | BLM (0.47) | BLMESR1ADRA2ASLC6A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2581081-A2 | Treatment of viral infections by modulation of host cell metabolic pathways | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2013-04-17 | — | — | EP | disclosed |
| EP-2572712-A2 | Treatment of viral infections by modulation of host cell metabolic pathways | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2013-03-27 | — | — | EP | disclosed |