⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14819037 | 0.78 | ESR1 (0.33) | — | |
| SCHEMBL17011622 | 0.69 | — | — | |
| SCHEMBL10319313 | 0.66 | — | — | |
| SCHEMBL16479528 | 0.61 | — | — | |
| SCHEMBL29212241 | 0.60 | — | — | |
| SCHEMBL3994162 | 0.60 | ESR1 (0.37) | — | |
| SCHEMBL28355421 | 0.59 | ESR1 (0.35) | — | |
| SCHEMBL21044898 | 0.58 | ESR1 (0.30) | — | |
| SCHEMBL31598470 | 0.58 | ESR1 (0.34) | — | |
| SCHEMBL5980986 | 0.57 | GPR3 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448978-B1 | DUAL METALLOCENE CATALYST SYSTEMS FOR DECREASING MELT INDEX AND INCREASING POLYMER PRODUCTION RATES | CHEVRON PHILLIPS CHEMICAL CO (US) | 2016-05-18 | — | — | EP | disclosed |
| US-9169333-B2 | Dual metallocene catalyst systems for decreasing melt index and increasing polymer production rates | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2015-10-27 | — | — | US | disclosed |
| EP-2448977-B1 | THE USE OF HYDROGEN SCAVENGING CATALYSTS TO CONTROL POLYMER MOLECULAR WEIGHT AND HYDROGEN LEVELS IN A POLYMERIZATION REACTOR | CHEVRON PHILLIPS CHEMICAL CO (US) | 2015-08-19 | — | — | EP | disclosed |
| US-9040642-B2 | Catalyst systems containing a bridged metallocene | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2015-05-26 | — | — | US | disclosed |
| US-8835588-B2 | Use of hydrogen scavenging catalysts to control polymer molecular weight and hydrogen levels in a polymerization reactor | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2014-09-16 | — | — | US | disclosed |
| US-20140235804-A1 | Dual Metallocene Catalyst Systems for Decreasing Melt Index and Increasing Polymer Production Rates | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2014-08-21 | — | — | US | disclosed |
| US-20140057777-A1 | Catalyst Systems Containing a Bridged Metallocene | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2014-02-27 | — | — | US | disclosed |
| US-8501654-B2 | Use of hydrogen scavenging catalysts to control polymer molecular weight and hydrogen levels in a polymerization reactor | CHEVRON PHILIPS CHEMICAL COMPANY LP (US) | 2013-08-06 | — | — | US | disclosed |
| US-8450436-B2 | Dual metallocene catalyst systems for decreasing melt index and increasing polymer production rates | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2013-05-28 | — | — | US | disclosed |
| US-20130079477-A1 | Dual Metallocene Catalyst Systems for Decreasing Melt Index and Increasing Polymer Production Rates | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2013-03-28 | — | — | US | disclosed |