SCHEMBL14819037

SCHEMBL14819037

C[Si](c1ccccc1)(C1C2C=CC=CC2C2C=CC=CC21)C1C2C=CC=CC2C2C=CC=CC21

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 1/20 0.33
▸ ESR2 Q92731 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17011621 0.82 — —
SCHEMBL14819038 0.78 — —
SCHEMBL10320730 0.70 — —
SCHEMBL16479528 0.69 — —
SCHEMBL3994162 0.67 ESR1 (0.37) ESR1ESR2
SCHEMBL28225522 0.66 ESR1 (0.44) ESR1ESR2
SCHEMBL28355421 0.65 ESR1 (0.35) ESR1ESR2
SCHEMBL31598470 0.64 ESR1 (0.34) ESR1ESR2
SCHEMBL21044968 0.62 ESR1 (0.33) ESR1ESR2
SCHEMBL2799324 0.61 ESR1 (0.44) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9169333-B2 Dual metallocene catalyst systems for decreasing melt index and increasing polymer production rates CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2015-10-27 — — US disclosed
US-9102821-B2 Catalysts for producing broad molecular weight distribution polyolefins in the absence of added hydrogen CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2015-08-11 — — US disclosed
US-9040642-B2 Catalyst systems containing a bridged metallocene CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2015-05-26 — — US disclosed
US-8835588-B2 Use of hydrogen scavenging catalysts to control polymer molecular weight and hydrogen levels in a polymerization reactor CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2014-09-16 — — US disclosed
US-20140235804-A1 Dual Metallocene Catalyst Systems for Decreasing Melt Index and Increasing Polymer Production Rates CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2014-08-21 — — US disclosed
US-20140057777-A1 Catalyst Systems Containing a Bridged Metallocene CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2014-02-27 — — US disclosed
US-8501654-B2 Use of hydrogen scavenging catalysts to control polymer molecular weight and hydrogen levels in a polymerization reactor CHEVRON PHILIPS CHEMICAL COMPANY LP (US) 2013-08-06 — — US disclosed
US-8450436-B2 Dual metallocene catalyst systems for decreasing melt index and increasing polymer production rates CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2013-05-28 — — US disclosed
US-20130079477-A1 Dual Metallocene Catalyst Systems for Decreasing Melt Index and Increasing Polymer Production Rates CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2013-03-28 — — US disclosed
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