Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1245247 | 0.87 | ELANE (0.84) | ELANECYP2C9 | |
| SCHEMBL14819126 | 0.84 | ELANE (0.67) | ELANECYP2C9 | |
| SCHEMBL6025100 | 0.81 | ELANE (0.76) | ELANECYP2C9 | |
| SCHEMBL394677 | 0.81 | ELANE (0.85) | ELANECYP2C9 | |
| SCHEMBL395186 | 0.81 | ELANE (1.00) | ELANECYP2C9 | |
| SCHEMBL391816 | 0.81 | ELANE (1.00) | ELANECYP2C9 | |
| SCHEMBL394085 | 0.81 | ELANE (0.85) | ELANECYP2C9 | |
| SCHEMBL4449580 | 0.81 | ELANE (0.85) | ELANECYP2C9 | |
| SCHEMBL3719477 | 0.80 | ELANE (0.86) | ELANECYP2C9 | |
| SCHEMBL122597 | 0.80 | ELANE (0.86) | ELANECYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546113-A1 | PYRIMIDINONE DERIVATIVES AS THERAPEUTIC AGENTS AGAINST ACUTE AND CHRONIC INFLAMMATORY, ISCHAEMIC AND REMODELLING PROCESSES | Bayer HealthCare AG (DE) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004024700-A1 | PYRIMIDINONE DERIVATIVES AS THERAPEUTIC AGENTS AGAINST ACUTE AND CHRONIC INFLAMMATORY, ISCHAEMIC AND REMODELLING PROCESSES | BAYER HEALTHCARE AG (DE) | 2004-03-25 | — | — | WO | disclosed |