Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.42 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.42 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.42 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1987047 | 0.85 | SLC7A5 (0.63) | SLC7A5ALDH1A1GAAGFERCYP4F2 | |
| SCHEMBL4394735 | 0.85 | SLC7A5 (0.62) | SLC7A5ALDH1A1GAAGFERCYP4F2 | |
| SCHEMBL18530377 | 0.85 | SLC7A5 (0.56) | SLC7A5ALDH1A1GAAGFERCYP4F2 | |
| SCHEMBL1628160 | 0.84 | CYP4A11 (0.57) | SLC7A5ALDH1A1GAAGFERCYP4F2 | |
| SCHEMBL14420121 | 0.84 | SLC7A5 (0.55) | SLC7A5ALDH1A1GAAGFERCYP4F2 | |
| SCHEMBL4579913 | 0.84 | SLC7A5 (0.58) | SLC7A5ALDH1A1GAAGFERCYP4F2 | |
| SCHEMBL28655132 | 0.84 | SLC7A5 (0.57) | SLC7A5ALDH1A1GAAGFERSIRT2 | |
| SCHEMBL12400239 | 0.83 | SLC7A5 (0.68) | SLC7A5ALDH1A1GAAGFERCYP4F2 | |
| SCHEMBL1630570 | 0.83 | SLC7A5 (0.54) | SLC7A5CYP4F2CYP4A11TLR7 | |
| SCHEMBL4577916 | 0.83 | CYP4A11 (0.64) | SLC7A5ALDH1A1GAAGFERCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2573069-A2 | Inhibitors of histone deacetylase and prodrugs thereof | MethylGene Inc. (CA) | 2013-03-27 | — | — | EP | disclosed |