Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.62 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.55 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.55 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12400239 | 0.94 | SLC7A5 (0.68) | SLC7A5CYP4F2CYP4A11HSP90AB1ALDH1A1 | |
| SCHEMBL28655132 | 0.91 | SLC7A5 (0.57) | SLC7A5CYP4F2CYP4A11HSP90AB1ALDH1A1 | |
| SCHEMBL8427611 | 0.91 | CYP4F2 (0.69) | SLC7A5CYP4F2CYP4A11HSP90AB1ALDH1A1 | |
| SCHEMBL14420123 | 0.91 | SLC7A5 (0.57) | SLC7A5CYP4F2CYP4A11HSP90AB1ALDH1A1 | |
| SCHEMBL30559747 | 0.90 | SLC7A5 (0.60) | SLC7A5CYP4F2CYP4A11HSP90AB1ALDH1A1 | |
| SCHEMBL27649231 | 0.90 | SLC7A5 (0.56) | SLC7A5CYP4F2CYP4A11HSP90AB1ALDH1A1 | |
| SCHEMBL6581681 | 0.90 | SLC7A5 (0.60) | SLC7A5CYP4F2CYP4A11HSP90AB1ALDH1A1 | |
| Iodide SCHEMBL5949324 | 0.90 | SLC7A5 (0.56) | SLC7A5CYP4F2CYP4A11HSP90AB1ALDH1A1 | |
| SCHEMBL3013114 | 0.88 | CHRM2 (0.57) | SLC7A5CYP4F2CYP4A11HSP90AB1ALDH1A1 | |
| Iodide SCHEMBL5949320 | 0.88 | SLC7A5 (0.55) | SLC7A5CYP4F2CYP4A11HSP90AB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553809-B2 | Fc receptor modulators and uses thereof | ILEXUS PTY LIMITED (AU) | 2009-06-30 | — | — | US | disclosed |
| US-20060057144-A1 | Fc receptor modulators and uses thereof | ILEXUS PTY LIMITED (AU) | 2006-03-16 | — | — | US | disclosed |
| US-6835753-B2 | Administering to the patient for inhibiting Fc receptor binding of immunoglobulin a compound selected from aromatic, heteroaromatic, cyclic, bicyclic and an amino acid derivative or salt | ILEXUS PTY LIMITED (AU) | 2004-12-28 | — | — | US | disclosed |
| US-20020061844-A1 | Administering to the patient for inhibiting Fc receptor binding of immunoglobulin a compound selected from aromatic, heteroaromatic, cyclic, bicyclic and an amino acid derivative or salt | ILEXUS PTY LIMITED | 2002-05-23 | — | — | US | disclosed |
| US-6355683-B1 | ANTIINFLAMMATORY AGENTS; AUTOIMMUNE DISEASE | ILEXUS PTY LIMITED (AU) | 2002-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020061844-A1 | Administering to the patient for inhibiting Fc receptor binding of immunoglobulin a compound selected from aromatic, heteroaromatic, cyclic, bicyclic and an amino acid derivative or salt | FCGR2A, FCGR1A, FCER2 | SLC7A5 176/4885CYP4F2 399/4885CYP4A11 489/4885 |
| US-20060057144-A1 | Fc receptor modulators and uses thereof | FCGR1A, FCER2, FCGR2A | SLC7A5 4227/4885CYP4F2 639/4885CYP4A11 938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.