Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RAC2 | P15153 | 1/20 | 0.33 |
| ▸ | RAC3 | P60763 | 1/20 | 0.33 |
| ▸ | CDC42 | P60953 | 1/20 | 0.33 |
| ▸ | RAC1 | P63000 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14822604 | 1.00 | KDM4E (0.50) | KDM4EL3MBTL1ATMMAPK8HDAC4 | |
| SCHEMBL802001 | 0.96 | KDM4E (0.46) | KDM4EL3MBTL1ATMMAPK8HDAC4 | |
| SCHEMBL16076353 | 0.96 | KDM4E (0.46) | KDM4EL3MBTL1ATMMAPK8HDAC4 | |
| SCHEMBL16940903 | 0.96 | KDM4E (0.46) | KDM4EL3MBTL1ATMMAPK8HDAC4 | |
| SCHEMBL14822438 | 0.96 | KDM4E (0.55) | KDM4EL3MBTL1ATMMAPK8HDAC4 | |
| SCHEMBL21374986 | 0.95 | KDM4E (0.45) | KDM4EL3MBTL1ATMMAPK8HDAC4 | |
| SCHEMBL14822534 | 0.95 | KDM4E (0.45) | KDM4EL3MBTL1ATMMAPK8HDAC4 | |
| SCHEMBL14822554 | 0.95 | KDM4E (0.45) | KDM4EL3MBTL1ATMMAPK8HDAC4 | |
| SCHEMBL12292005 | 0.95 | KDM4E (0.45) | KDM4EL3MBTL1ATMMAPK8HDAC4 | |
| SCHEMBL16282983 | 0.95 | KDM4E (0.45) | KDM4EL3MBTL1ATMMAPK8HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9818948-B2 | Carbazole derivatives for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2017-11-14 | — | — | US | disclosed |
| US-9818948-B2 | Carbazole derivatives for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2017-11-14 | — | — | US | disclosed |
| US-20140225046-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-08-14 | — | — | US | disclosed |
| US-20140225046-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-08-14 | — | — | US | disclosed |
| WO-2013041176-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2013-03-28 | — | — | WO | disclosed |