SCHEMBL16282983

SCHEMBL16282983

CC1(C)c2ccccc2-c2cc3c4ccccc4n(-c4ccc5c(c4)c4ccccc4n5-c4ccc5c(c4)c4ccccc4n5-c4ccccc4)c3cc21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.45
ATM Q13315 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
PGR P06401 7/20 0.35
HDAC4 P56524 1/20 0.32
MAPK8 P45983 1/20 0.32
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31
HBB P68871 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
RAC2 P15153 1/20 0.31
RAC3 P60763 1/20 0.31
CDC42 P60953 1/20 0.31
RAC1 P63000 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14822554 1.00 KDM4E (0.45) KDM4EATML3MBTL1PGRHDAC4
SCHEMBL21374986 1.00 KDM4E (0.45) KDM4EATML3MBTL1PGRHDAC4
SCHEMBL12292005 1.00 KDM4E (0.45) KDM4EATML3MBTL1PGRHDAC4
SCHEMBL14822534 1.00 KDM4E (0.45) KDM4EATML3MBTL1PGRHDAC4
SCHEMBL14960776 0.95 KDM4E (0.41) KDM4EATML3MBTL1PGRHDAC4
SCHEMBL14822265 0.95 KDM4E (0.41) KDM4EATML3MBTL1PGRHDAC4
SCHEMBL18062348 0.95 KDM4E (0.41) KDM4EATML3MBTL1PGR
SCHEMBL14822256 0.95 KDM4E (0.41) KDM4EATML3MBTL1PGRHDAC4
SCHEMBL17245591 0.95 KDM4E (0.45) KDM4EATML3MBTL1PGRHDAC4
SCHEMBL14822430 0.95 KDM4E (0.45) KDM4EATML3MBTL1PGRHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140364625-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM & HAAS ELECT MAT (KR) 2014-12-11 US disclosed
US-20140364625-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM & HAAS ELECT MAT (KR) 2014-12-11 US disclosed