Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 19/20 | 0.65 |
| ▸ | MMP2 | P08253 | 18/20 | 0.65 |
| ▸ | MMP3 | P08254 | 5/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 4/20 | 0.45 |
| ▸ | MMP8 | P22894 | 4/20 | 0.45 |
| ▸ | MMP14 | P50281 | 4/20 | 0.45 |
| ▸ | MMP25 | Q9NPA2 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14822934 | 0.91 | MMP2 (0.55) | MMP9MMP2MMP3MMP13MMP1 | |
| SCHEMBL13409998 | 0.89 | MMP9 (0.61) | MMP9MMP2MMP3MMP13MMP1 | |
| SCHEMBL3691573 | 0.89 | MMP9 (0.61) | MMP9MMP2MMP3MMP13MMP1 | |
| SCHEMBL14822950 | 0.88 | MMP9 (0.50) | MMP9MMP2MMP3MMP13MMP1 | |
| SCHEMBL14823011 | 0.86 | MMP9 (0.67) | MMP9MMP2MMP3MMP13MMP1 | |
| Trifluoroacetic Acid SCHEMBL3683028 | 0.83 | MMP9 (0.55) | MMP9MMP2MMP3MMP13MMP1 | |
| Trifluoroacetic Acid SCHEMBL3683023 | 0.83 | MMP9 (0.55) | MMP9MMP2MMP3MMP13MMP1 | |
| SCHEMBL3688503 | 0.80 | MMP2 (0.52) | MMP9MMP2MMP3MMP13MMP1 | |
| SCHEMBL13409993 | 0.80 | MMP2 (0.52) | MMP9MMP2MMP3MMP13MMP1 | |
| SCHEMBL13272367 | 0.79 | MMP9 (0.63) | MMP9MMP2MMP3MMP13MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410150-B2 | Inhibitors of carnitine palmitoyltransferase and treating cancer | UNIVERSITY HEALTH NETWORK (CA) | 2013-04-02 | — | — | US | disclosed |