Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | FABP6 | P51161 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10159205 | 0.79 | MAPT (0.39) | ALDH1A1GAAMAPTHSD17B10ADRA2A | |
| SCHEMBL3295033 | 0.79 | ALDH1A1 (0.46) | ALDH1A1GAAMAPTHSD17B10ADRA2A | |
| SCHEMBL15996968 | 0.79 | ALDH1A1 (0.39) | ALDH1A1GAAMAPTHSD17B10ADRA2A | |
| SCHEMBL3295929 | 0.79 | GAA (0.39) | ALDH1A1GAAMAPTHSD17B10ADRA2A | |
| SCHEMBL13736849 | 0.75 | ALDH1A1 (0.39) | ALDH1A1GAAMAPTHSD17B10ADRA2A | |
| SCHEMBL12533362 | 0.75 | ALDH1A1 (0.39) | ALDH1A1GAAMAPTHSD17B10ADRA2A | |
| SCHEMBL10157297 | 0.75 | ALDH1A1 (0.39) | ALDH1A1GAAMAPTHSD17B10ADRA2A | |
| SCHEMBL16404623 | 0.70 | MAPT (0.43) | ALDH1A1GAAMAPTHSD17B10ADRA2A | |
| SCHEMBL252182 | 0.69 | ADRA2A (0.35) | ALDH1A1GAAMAPTHSD17B10ADRA2A | |
| SCHEMBL1191653 | 0.69 | ADRA2A (0.42) | ALDH1A1GAAMAPTHSD17B10ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2574610-A1 | Inhibitors of human immonodeficiency virus replication | GILEAD SCIENCES, INC. (US) | 2013-04-03 | — | — | EP | disclosed |