Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | AIP | O00170 | 1/20 | 0.51 |
| ▸ | SGTA | O43765 | 1/20 | 0.51 |
| ▸ | TOMM70 | O94826 | 1/20 | 0.51 |
| ▸ | STIP1 | P31948 | 1/20 | 0.51 |
| ▸ | PPP5C | P53041 | 1/20 | 0.51 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.51 |
| ▸ | PPID | Q08752 | 1/20 | 0.51 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.51 |
| ▸ | FKBP8 | Q14318 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13781560 | 0.92 | ALDH1A1 (0.56) | ALDH1A1HTTSMN1; SMN2RECQLMAPT | |
| SCHEMBL13781600 | 0.87 | HCAR2 (0.56) | ALDH1A1HTTSMN1; SMN2RECQLMAPT | |
| SCHEMBL23413257 | 0.76 | ALDH1A1 (0.83) | ALDH1A1HTTSMN1; SMN2MAPTHPGD | |
| SCHEMBL14825388 | 0.74 | FLT3 (0.79) | ALDH1A1HTTSMN1; SMN2MAPTHPGD | |
| SCHEMBL1800640 | 0.73 | ALDH1A1 (0.72) | ALDH1A1HTTSMN1; SMN2MAPTHPGD | |
| SCHEMBL1954227 | 0.73 | TSHR (0.45) | ALDH1A1HTTSMN1; SMN2MAPTHPGD | |
| SCHEMBL13781563 | 0.72 | HCAR2 (0.52) | SMN1; SMN2POLBCNR2NPC1RAB9A | |
| SCHEMBL31541275 | 0.71 | ALDH1A1 (1.00) | ALDH1A1HTTSMN1; SMN2MAPTHPGD | |
| SCHEMBL7003055 | 0.71 | AIP (0.74) | ALDH1A1HTTSMN1; SMN2RECQLMAPT | |
| SCHEMBL21612947 | 0.71 | ALDH1A1 (0.61) | ALDH1A1HTTMAPTHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130085133-A1 | ANTI-VIRAL TREATMENT AND ASSAY TO SCREENFOR ANTI-VIRAL AGENT | Sourthern Research Institute Office of Commercialization and Intellectual Prop. (US) | 2013-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130085133-A1 | ANTI-VIRAL TREATMENT AND ASSAY TO SCREENFOR ANTI-VIRAL AGENT | MAVS, SNRPE, LONP1 | ALDH1A1 3082/4885HTT 4221/4885SMN1; SMN2 1270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.