Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.66 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.52 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2950259 | 0.85 | HIF1A (0.70) | HIF1AEPAS1MAPTKMT2AMEN1 | |
| SCHEMBL16082972 | 0.80 | ATF4 (0.71) | MAPTKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL16082952 | 0.76 | ATF4 (0.82) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL2950201 | 0.76 | NPC1 (0.69) | HIF1AEPAS1MAPTKMT2AMEN1 | |
| SCHEMBL2957047 | 0.76 | HIF1A (0.65) | HIF1AEPAS1MAPTKMT2AMEN1 | |
| SCHEMBL19134192 | 0.74 | KMT2A (0.68) | MAPTKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL23455785 | 0.74 | ATF4 (0.61) | MAPTKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL17658725 | 0.74 | ATF4 (0.61) | MAPTKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL23455784 | 0.74 | ATF4 (0.61) | MAPTKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL2947489 | 0.73 | MEN1 (0.78) | HIF1AEPAS1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130085133-A1 | ANTI-VIRAL TREATMENT AND ASSAY TO SCREENFOR ANTI-VIRAL AGENT | Sourthern Research Institute Office of Commercialization and Intellectual Prop. (US) | 2013-04-04 | — | — | US | disclosed |
| US-20130085133-A1 | ANTI-VIRAL TREATMENT AND ASSAY TO SCREENFOR ANTI-VIRAL AGENT | Sourthern Research Institute Office of Commercialization and Intellectual Prop. (US) | 2013-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130085133-A1 | ANTI-VIRAL TREATMENT AND ASSAY TO SCREENFOR ANTI-VIRAL AGENT | MAVS, SNRPE, LONP1 | KCNH2 4779/4885SMYD3 3127/4885HIF1A 852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.