Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K11 | Q16584 | 11/20 | 0.60 |
| ▸ | MAP3K9 | P80192 | 10/20 | 0.60 |
| ▸ | MAP3K10 | Q02779 | 7/20 | 0.60 |
| ▸ | KDR | P35968 | 4/20 | 0.60 |
| ▸ | FLT1 | P17948 | 3/20 | 0.60 |
| ▸ | FLT4 | P35916 | 3/20 | 0.60 |
| ▸ | DLK1 | P80370 | 1/20 | 0.60 |
| ▸ | PAK3 | O75914 | 2/20 | 0.59 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.57 |
| ▸ | PRKCQ | Q04759 | 5/20 | 0.56 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.56 |
| ▸ | PRKCG | P05129 | 3/20 | 0.56 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.56 |
| ▸ | PRKCA | P17252 | 3/20 | 0.56 |
| ▸ | PKN1 | Q16512 | 2/20 | 0.56 |
| ▸ | PRKCB | P05771 | 2/20 | 0.56 |
| ▸ | PRKCH | P24723 | 2/20 | 0.56 |
| ▸ | PRKCI | P41743 | 2/20 | 0.56 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.56 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14825413 | 0.92 | PAK3 (0.68) | MAP3K11MAP3K9MAP3K10KDRFLT1 | |
| SCHEMBL16437780 | 0.83 | PRKCQ (0.76) | MAP3K11MAP3K9MAP3K10KDRFLT1 | |
| SCHEMBL1649555 | 0.80 | MAP3K11 (0.67) | MAP3K11MAP3K9MAP3K10KDRFLT1 | |
| SCHEMBL13140134 | 0.79 | MAP3K11 (0.93) | MAP3K11MAP3K9MAP3K10KDRFLT1 | |
| SCHEMBL13142263 | 0.79 | MAP3K11 (0.93) | MAP3K11MAP3K9MAP3K10KDRFLT1 | |
| SCHEMBL5964631 | 0.76 | MAP3K11 (0.86) | MAP3K11MAP3K9MAP3K10KDRFLT1 | |
| SCHEMBL8280372 | 0.76 | MAP3K11 (0.79) | MAP3K11MAP3K9MAP3K10KDRFLT1 | |
| Cep-1347 SCHEMBL8263437 | 0.75 | MAP3K11 (1.00) | MAP3K11MAP3K9MAP3K10KDRFLT1 | |
| Cep-1347 SCHEMBL30198505 | 0.75 | MAP3K11 (1.00) | MAP3K11MAP3K9MAP3K10KDRFLT1 | |
| Cep-1347 SCHEMBL29381680 | 0.75 | MAP3K11 (1.00) | MAP3K11MAP3K9MAP3K10KDRFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8771682-B2 | Methods and compositions for reducing interleukin-4 or interleukin-13 signaling | Technische Universtität Dresden (DE) | 2014-07-08 | — | — | US | disclosed |
| US-20130084275-A1 | Methods and Compositions for Reducing Interleukin-4 or Interleukin-13 Signaling | TECHNISCHE UNIVERSITAT DRESDEN (DE) | 2013-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130084275-A1 | Methods and Compositions for Reducing Interleukin-4 or Interleukin-13 Signaling | IL4, IL2RA, STAT6 | MAP3K11 185/4885MAP3K9 293/4885MAP3K10 232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.