SCHEMBL1482804

SCHEMBL1482804

c1ccc(-c2ccc(-c3ccc4c(c3)Cc3ccccc3-4)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.57
ALDH1A1 P00352 3/20 0.57
NPC1 O15118 2/20 0.57
LMNA P02545 2/20 0.57
RAB9A P51151 2/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
KDM4E B2RXH2 1/20 0.57
HPGD P15428 1/20 0.57
TDP2 O95551 1/20 0.56
SRD5A2 P31213 1/20 0.55
MMP12 P39900 1/20 0.54
MMP13 P45452 1/20 0.54
CNR1 P21554 1/20 0.50
CYP1A2 P05177 3/20 0.47
CYP3A4 P08684 2/20 0.47
CYP2C19 P33261 1/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
ATM Q13315 2/20 0.47
NPSR1 Q6W5P4 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1666630 1.00 MAPT (0.57) MAPTALDH1A1NPC1LMNARAB9A
SCHEMBL30172496 1.00 MAPT (0.57) MAPTALDH1A1NPC1LMNARAB9A
SCHEMBL3414807 0.94 ALDH1A1 (0.63) MAPTALDH1A1NPC1LMNARAB9A
SCHEMBL30395577 0.94 ALDH1A1 (0.63) MAPTALDH1A1NPC1LMNARAB9A
SCHEMBL1482920 0.94 TDP2 (0.61) MAPTALDH1A1NPC1LMNARAB9A
SCHEMBL3136254 0.94 TDP2 (0.61) MAPTALDH1A1NPC1LMNARAB9A
SCHEMBL29569358 0.94 TDP2 (0.61) MAPTALDH1A1NPC1LMNARAB9A
SCHEMBL27614921 0.92 NPC1 (0.52) MAPTALDH1A1NPC1LMNARAB9A
SCHEMBL30831157 0.91 TDP2 (0.59) MAPTALDH1A1NPC1LMNARAB9A
SCHEMBL7139324 0.89 TDP2 (0.58) MAPTALDH1A1NPC1LMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293856-B2 Process for preparing olefin polymer using mixed catalyst MITSUI CHEMICALS, INC. (JP) 2012-10-23 US disclosed
US-20110077369-A1 PROCESS FOR PREPARING OLEFIN POLYMER USING MIXED CATALYST MITSU CHEMICALS, INC. 2011-03-31 US disclosed