SCHEMBL14828366

SCHEMBL14828366

c1ccc2c(-c3ccc4[nH]c5ccc(-c6cccc7ccccc67)cc5c4c3)cccc2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.47
ACMSD Q8TDX5 1/20 0.47
AHR P35869 1/20 0.45
CA12 O43570 2/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA9 Q16790 2/20 0.44
KDM4E B2RXH2 2/20 0.44
ALDH1A1 P00352 2/20 0.44
HSD17B10 Q99714 2/20 0.44
LMNA P02545 1/20 0.44
BCHE P06276 1/20 0.43
ALK Q9UM73 1/20 0.43
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
TLR8 Q9NR97 1/20 0.42
TLR7 Q9NYK1 1/20 0.42
ALPL P05186 1/20 0.42
GAA P10253 1/20 0.42
CDK4 P11802 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3419553 0.96 AHR (0.52) MCL1ACMSDAHRCA12CA1
SCHEMBL16745241 0.93 CDK4 (0.51) MCL1ACMSDAHRCA12CA1
SCHEMBL17154795 0.93 CA12 (0.51) MCL1ACMSDAHRCA12CA1
SCHEMBL18028385 0.92 AHR (0.47) MCL1ACMSDAHRCA12CA1
SCHEMBL18428557 0.90 CA12 (0.49) AHRCA12CA1CA2CA9
SCHEMBL30030358 0.90 CA12 (0.49) AHRCA12CA1CA2CA9
SCHEMBL3339205 0.90 CA12 (0.52) MCL1ACMSDCA12CA1CA2
SCHEMBL22894081 0.89 CDK4 (0.54) MCL1ACMSDCA12CA1CA2
SCHEMBL28304527 0.88 CDK4 (0.49) MCL1ACMSDAHRCA12CA1
SCHEMBL21709343 0.87 KIF11 (0.60) MCL1ACMSDCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200131150-A1 CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE SAME AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-04-30 US disclosed
US-20200131150-A1 CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE SAME AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-04-30 US disclosed
EP-3644385-A1 CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE SAME AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2020-04-29 EP disclosed
EP-3644385-A1 CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE SAME AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2020-04-29 EP disclosed
WO-2020062375-A1 1,2,4-THIADIAZOLE COMPOUNDS AND PREPARATION METHOD THEREFOR AND USE THEREOF 武汉尚赛光电科技有限公司 2020-04-02 WO disclosed
CN-106866672-B A kind of preparation method and applications of OLED material 中节能万润股份有限公司 2018-12-25 CN disclosed
CN-106866672-A A kind of preparation method and applications of new OLED material 中节能万润股份有限公司 2017-06-20 CN disclosed
US-9394280-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-07-19 US disclosed
CN-103833727-B The S that soluble branch replaces, S-dioxo-dibenzothiophene base blue light molecular glass material and preparation method thereof and application SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) 2016-03-02 CN disclosed
US-20150171343-A1 BLUE FLUORESCENT ORGANIC MATERIAL AND ORGANIC LIGHT EMITTING DIODE PANEL THEREOF SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD (CN) 2015-06-18 US disclosed
US-20150171343-A1 BLUE FLUORESCENT ORGANIC MATERIAL AND ORGANIC LIGHT EMITTING DIODE PANEL THEREOF SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD (CN) 2015-06-18 US disclosed
US-20150171343-A1 BLUE FLUORESCENT ORGANIC MATERIAL AND ORGANIC LIGHT EMITTING DIODE PANEL THEREOF SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD (CN) 2015-06-18 US disclosed
US-9059413-B1 Blue fluorescent organic material and organic light emitting diode panel thereof SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO LTD (CN) 2015-06-16 US disclosed
US-9059413-B1 Blue fluorescent organic material and organic light emitting diode panel thereof SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO LTD (CN) 2015-06-16 US disclosed
US-9059413-B1 Blue fluorescent organic material and organic light emitting diode panel thereof SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO LTD (CN) 2015-06-16 US disclosed
CN-103666459-B Blue-fluorescence organic material and organic light emitting diode panel employing same SHENZHEN CHINA STAR OPTOELECT 2015-01-21 CN disclosed
CN-103833727-A Soluble dendron substituted S,S-dioxo-dibenzothiophene based blue-light molecular glass material as well as preparation method and application thereof UNIV SOUTH CHINA TECH 2014-06-04 CN disclosed
CN-103666459-A Blue-fluorescence organic material and organic light emitting diode panel employing same SHENZHEN HUAXING OPTOELECT TEC 2014-03-26 CN disclosed
US-20130082591-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-04-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200131150-A1 CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE SAME AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CCNT1, CCNA1, CCNE2 MCL1 865/4885ACMSD 3204/4885AHR 1575/4885
US-20130082591-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE AHR, CYP1A1, ARNT MCL1 4080/4885ACMSD 1898/4885AHR 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.