SCHEMBL14829313

SCHEMBL14829313

NCC1(CNC(=O)O)CC1

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.42
TSHR P16473 2/20 0.42
USP2 O75604 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
BLM P54132 1/20 0.42
CACNA2D1 P54289 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CYP2D6 P10635 3/20 0.33
CYP2C19 P33261 2/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2770951 0.91 USP2 (0.48) CYP1A2TSHRUSP2ALDH1A1LMNA
SCHEMBL8211734 0.90 LMNA (0.57) CYP1A2TSHRUSP2ALDH1A1LMNA
SCHEMBL15941627 0.81 USP2 (0.34) CYP1A2TSHRUSP2ALDH1A1LMNA
SCHEMBL4287905 0.79 CNR2 (0.33) CYP2D6CYP2C19
SCHEMBL25217168 0.76
SCHEMBL8182036 0.74 LMNA (0.43) CYP1A2TSHRUSP2ALDH1A1LMNA
SCHEMBL23459103 0.72 KMT2A (0.31) ALDH1A1
SCHEMBL25353404 0.72 EPHX2 (0.31)
SCHEMBL13162528 0.71 HCRTR2 (0.42) TSHRALDH1A1
SCHEMBL99571 0.71 CNR2 (0.40) CYP1A2TSHRUSP2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357133-A1 NANOMATERIALS COMPRISING CARBONATES BEAM THERAPEUTICS INC. 2023-11-09 US disclosed
EP-4262818-A1 NANOMATERIALS COMPRISING CARBONATES Beam Therapeutics Inc. (US) 2023-10-25 EP disclosed
WO-2023154818-A1 MUCOSAL ADMINISTRATION METHODS AND FORMULATIONS MODERNATX, INC. (US) 2023-08-17 WO disclosed
WO-2023076598-A1 LIPID AMINES MODERNATX, INC. (US) 2023-05-04 WO disclosed
WO-2022140239-A1 NANOMATERIALS COMPRISING CARBONATES BEAM THERAPEUTICS INC. (US) 2022-06-30 WO disclosed
EP-3655406-A1 SUBSTITUTED PYRROLOPYRIDINE-DERIVATIVES Bayer Pharma Aktiengesellschaft (DE) 2020-05-27 EP disclosed
WO-2019016071-A1 SUBSTITUTED PYRROLOPYRIDINE-DERIVATIVES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2019-01-24 WO disclosed
EP-2953954-B1 MACROCYCLIC COMPOUNDS AS HCV ENTRY INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2017-11-15 EP disclosed
US-9624245-B2 Macrocyclic compounds as HCV entry inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2017-04-18 US disclosed
EP-2760872-B1 COMPOUNDS FOR THE TREATMENT OF HEPATITIS C BRISTOL MYERS SQUIBB CO (US) 2016-04-13 EP disclosed
EP-2953954-A1 MACROCYCLIC COMPOUNDS AS HCV ENTRY INHIBITORS Bristol-Myers Squibb Company (US) 2015-12-16 EP disclosed
WO-2014123894-A1 MACROCYCLIC COMPOUNDS AS HCV ENTRY INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2014-08-14 WO disclosed
EP-2760872-A1 COMPOUNDS FOR THE TREATMENT OF HEPATITIS C Bristol-Myers Squibb Company (US) 2014-08-06 EP disclosed
WO-2013048995-A1 COMPOUNDS FOR THE TREATMENT OF HEPATITIS C BRISTOL-MYERS SQUIBB COMPANY (US) 2013-04-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357133-A1 NANOMATERIALS COMPRISING CARBONATES PHOSPHO1, CA13, SGMS2 CYP1A2 2579/4885TSHR 4434/4885USP2 3475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.