Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.61 |
| ▸ | CES1 | P23141 | 4/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27479870 | 0.86 | CES2 (0.59) | CES2CES1L3MBTL1SNCADGAT1 | |
| SCHEMBL6518724 | 0.85 | CES2 (0.57) | CES2CES1L3MBTL1SNCAALDH1A1 | |
| Bromide SCHEMBL2097705 | 0.83 | CES2 (0.56) | CES2CES1L3MBTL1SNCAALDH1A1 | |
| SCHEMBL7806345 | 0.82 | CES2 (0.63) | CES2CES1L3MBTL1SNCANPC1 | |
| SCHEMBL9340459 | 0.80 | CES2 (0.61) | CES2CES1L3MBTL1SNCARAB9A | |
| SCHEMBL8292394 | 0.80 | CES2 (0.61) | CES2CES1L3MBTL1SNCAALDH1A1 | |
| SCHEMBL9148939 | 0.78 | CES2 (0.59) | CES2CES1L3MBTL1SNCANPC1 | |
| SCHEMBL2562024 | 0.78 | CES2 (0.64) | CES2CES1L3MBTL1SNCAALDH1A1 | |
| SCHEMBL10454903 | 0.78 | CES2 (0.59) | CES2CES1L3MBTL1SNCANPC1 | |
| SCHEMBL7804388 | 0.78 | CES2 (0.59) | CES2CES1L3MBTL1SNCAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013049585-A1 | ARYLSUBSTITUTED THIAZOLOTRIAZOLES AND THIAZOLOIMIDAZOLES | HENGRUI (USA), LTD. (US) | 2013-04-04 | — | — | WO | disclosed |