Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.63 |
| ▸ | CES1 | P23141 | 4/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27479870 | 0.84 | CES2 (0.59) | CES2CES1L3MBTL1SNCANPC1 | |
| SCHEMBL10454903 | 0.84 | CES2 (0.59) | CES2CES1L3MBTL1SNCANPC1 | |
| SCHEMBL7804388 | 0.84 | CES2 (0.59) | CES2CES1L3MBTL1SNCAMAPK14 | |
| SCHEMBL29669019 | 0.83 | CES2 (0.63) | CES2CES1 | |
| SCHEMBL20237914 | 0.83 | CES2 (0.63) | CES2CES1 | |
| SCHEMBL9340459 | 0.82 | CES2 (0.61) | CES2CES1L3MBTL1SNCARAB9A | |
| SCHEMBL3501242 | 0.82 | CES2 (0.43) | CES2CES1ALDH1A1HTT | |
| SCHEMBL8292394 | 0.82 | CES2 (0.61) | CES2CES1L3MBTL1SNCAMAPK14 | |
| SCHEMBL14829993 | 0.82 | CES2 (0.61) | CES2CES1L3MBTL1SNCANPC1 | |
| SCHEMBL940243 | 0.80 | CES2 (0.64) | CES2CES1L3MBTL1SNCAMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0814079-B1 | Triazole derivative or salt thereof | SS PHARMACEUTICAL CO (JP) | 2001-03-28 | — | — | EP | disclosed |
| EP-0117100-B1 | TRIAZOLE ANTIFUNGAL AGENTS | Pfizer Limited (GB) | 1986-12-10 | — | — | EP | disclosed |
| US-4616026-A | Antifungal 2-aryl-1,1-difluoro-3-(1H-1,2,4-triazol-1-yl)2-propanols | PFIZER INC. (US) | 1986-10-07 | — | — | US | disclosed |
| EP-0117100-A1 | Triazole antifungal agents | Pfizer Limited (GB) | 1984-08-29 | — | — | EP | disclosed |