SCHEMBL14830268

SCHEMBL14830268

CC1=Cc2ccccc2C1[Hf](=[SiH2])(c1ccccc1)(c1ccccc1)C1C(C)=Cc2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL818743 0.98 LMNA (0.31) LMNA
Hydrochloric Acid SCHEMBL7935728 0.85 LMNA (0.31) LMNA
Hydrochloric Acid SCHEMBL4463623 0.81 SLC6A2 (0.33)
SCHEMBL7645858 0.80 LMNA (0.31) LMNA
Hydrochloric Acid SCHEMBL818447 0.79 LMNA (0.31) LMNA
Hydrochloric Acid SCHEMBL7933059 0.78 LMNA (0.31) LMNA
Hydrochloric Acid SCHEMBL7935416 0.77 BRD4 (0.31)
SCHEMBL7626260 0.77 LMNA (0.31) LMNA
Hydrochloric Acid SCHEMBL7938652 0.77 LMNA (0.31) LMNA
SCHEMBL7634767 0.77 LMNA (0.33) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2760958-B1 SYSTEMS, METHODS AND COMPOSITIONS FOR PRODUCTION OF TIE-LAYER ADHESIVES EQUISTAR CHEM LP (US) 2020-08-12 EP disclosed
EP-2760958-A1 SYSTEMS, METHODS AND COMPOSITIONS FOR PRODUCTION OF TIE-LAYER ADHESIVES Equistar Chemicals, LP (US) 2014-08-06 EP disclosed
WO-2013049786-A1 SYSTEMS, METHODS AND COMPOSITIONS FOR PRODUCTION OF TIE-LAYER ADHESIVES EQUISTAR CHEMICALS, LP (US) 2013-04-04 WO disclosed