SCHEMBL7645858

SCHEMBL7645858

CC1=Cc2ccccc2C1[Hf](C)(C)(=[SiH2])C1C(C)=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
DRD2 P14416 1/20 0.30
DRD4 P21917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL818447 0.98 LMNA (0.31) LMNAALDH1A1SMN1; SMN2TDP1
Hydrochloric Acid SCHEMBL7935728 0.82 LMNA (0.31) LMNA
SCHEMBL1834547 0.80
SCHEMBL14830268 0.80 LMNA (0.32) LMNA
Hydrochloric Acid SCHEMBL7933190 0.79 LMNA (0.31) LMNAALDH1A1SMN1; SMN2TDP1
Hydrochloric Acid SCHEMBL818478 0.79
Hydrochloric Acid SCHEMBL6471349 0.79 ALDH1A1 (0.31) ALDH1A1SMN1; SMN2TDP1
Hydrochloric Acid SCHEMBL818743 0.79 LMNA (0.31) LMNA
Bromide SCHEMBL817479 0.79 ALDH1A1 (0.31) ALDH1A1SMN1; SMN2TDP1
SCHEMBL17415133 0.78 SLC6A2 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6136993-A CONTACTING IN GROUP 4 METAL COMPLEX OR ITS LEWIS BASE ADDUCT WITH METAL COMPLEX, RECOVERING RESULTING PRODUCT THE DOW CHEMICAL COMPANY (US) 2000-10-24 US claimed
US-6433110-B1 USING COORDINATION CATALYST BASELL POLYOLEFINE GMBH (DE) 2002-08-13 US disclosed
US-6350829-B1 SOLID CATALYST SUPPORT AND METALLOCENE CATALYST COMPLEX BASELL POLYOLEFIN GMBH (DE) 2002-02-26 US disclosed
US-20010001796-A1 PROCESS FOR PRODUCING POLYMERS OF ALKENES BY SUSPENSION POLYMERISATION JOHN LYNCH 2001-05-24 US disclosed
US-6136993-A CONTACTING IN GROUP 4 METAL COMPLEX OR ITS LEWIS BASE ADDUCT WITH METAL COMPLEX, RECOVERING RESULTING PRODUCT THE DOW CHEMICAL COMPANY (US) 2000-10-24 US disclosed
US-6084115-A METAL DIENE-CONTAINING COMPLEXES BY REACTION WITH THE DIVALENT DERIVATIVE OF A BRIDGED BIDENTATE LIGAND; METALLOCENES; RACEMIC ISOMER USED TO PREPARE ISOTACTIC POLYOLEFINS, E.G., CRYSTALLINE POLYPROPYLENE. THE DOW CHEMICAL COMPANY (US) 2000-07-04 US disclosed
EP-0730003-B1 Polypropylene resin composition and molded product TOSOH CORP (JP) 1997-12-29 EP disclosed
EP-0730003-A1 Polypropylene resin composition and molded product Tosoh Corporation (JP) 1996-09-04 EP disclosed