Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.43 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14830349 | 1.00 | GPR84 (0.59) | GPR84FFAR1FFAR4NFKB1TRPV1 | |
| SCHEMBL15374693 | 0.85 | GPR84 (0.63) | GPR84FFAR1FFAR4NFKB1TRPV1 | |
| SCHEMBL23554231 | 0.85 | GPR84 (0.63) | GPR84FFAR1FFAR4NFKB1TRPV1 | |
| SCHEMBL14830348 | 0.82 | GPR84 (0.59) | GPR84FFAR1FFAR4NFKB1TRPV1 | |
| SCHEMBL14831024 | 0.82 | GPR84 (0.59) | GPR84FFAR1FFAR4NFKB1TRPV1 | |
| SCHEMBL12324209 | 0.78 | GPR84 (0.57) | GPR84FFAR1FFAR4LCKPPARD | |
| SCHEMBL19388616 | 0.77 | CA2 (0.52) | GPR84FFAR1LCKPPARDZDHHC20 | |
| Benzene SCHEMBL3447636 | 0.76 | GPR84 (0.92) | GPR84FFAR1FFAR4NFKB1TRPV1 | |
| SCHEMBL22274658 | 0.76 | CA2 (0.55) | GPR84FFAR1LCKPPARDZDHHC20 | |
| SCHEMBL25190812 | 0.76 | GPR84 (0.92) | GPR84FFAR1FFAR4NFKB1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140309275-A1 | Sphingosine Analogs, Compositions, and Methods Related Thereto | UNIV EMORY (US) | 2014-10-16 | — | — | US | disclosed |
| EP-2760820-A2 | SPHINGOSINE ANALOGS, COMPOSITIONS, AND METHODS RELATED THERETO | Emory University (US) | 2014-08-06 | — | — | EP | disclosed |
| WO-2013049280-A2 | SPHINGOSINE ANALOGS, COMPOSITIONS, AND METHODS RELATED THERETO | EMORY UNIVERSITY (US) | 2013-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140309275-A1 | Sphingosine Analogs, Compositions, and Methods Related Thereto | SPHK1, S1PR1, S1PR2 | GPR84 1521/4885FFAR1 755/4885FFAR4 1594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.