Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | TFPI2 | P48307 | 4/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.34 |
| ▸ | PPM1B | O75688 | 3/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.33 |
| ▸ | PPP1CC | P36873 | 3/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1859238 | 1.00 | LMNA (0.41) | LMNAPLGPLATTFPI2PMP22 | |
| SCHEMBL27516610 | 0.95 | LMNA (0.40) | LMNAPLGPLATTFPI2PMP22 | |
| Ethylene Glycol SCHEMBL6404800 | 0.87 | TFPI2 (0.45) | LMNAPLGPLATTFPI2PMP22 | |
| Ethylene Glycol SCHEMBL259159 | 0.87 | TFPI2 (0.45) | LMNAPLGPLATTFPI2PMP22 | |
| SCHEMBL4948347 | 0.87 | TFPI2 (0.52) | LMNAPLGPLATTFPI2PMP22 | |
| SCHEMBL2184024 | 0.87 | TFPI2 (0.52) | LMNAPLGPLATTFPI2PMP22 | |
| SCHEMBL7263479 | 0.87 | TFPI2 (0.52) | LMNAPLGPLATTFPI2PMP22 | |
| SCHEMBL4098788 | 0.87 | TFPI2 (0.52) | LMNAPLGPLATTFPI2PMP22 | |
| SCHEMBL2726787 | 0.87 | TFPI2 (0.52) | LMNAPLGPLATTFPI2PMP22 | |
| SCHEMBL4109815 | 0.87 | TFPI2 (0.52) | LMNAPLGPLATTFPI2PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014152543-A2 | OXETANE-CONTAINING COMPOUNDS AND COMPOSITIONS THEREOF | Henkel IP & Holding GmbH (DE) | 2014-09-25 | — | — | WO | disclosed |
| US-20140264165-A1 | OXETANE-CONTAINING COMPOUNDS AND COMPOSITIONS THEREOF | HENKEL CORPORATION (US) | 2014-09-18 | — | — | US | disclosed |
| EP-2760910-A2 | OXETANE-CONTAINING COMPOUNDS AND COMPOSITIONS THEREOF | Henkel AG&Co. KGAA (DE) | 2014-08-06 | — | — | EP | disclosed |
| US-20140209951-A1 | OXETANE-CONTAINING COMPOUNDS AND COMPOSITIONS THEREOF | Henkel IP & Holding GmbH (DE) | 2014-07-31 | — | — | US | disclosed |
| WO-2013049154-A2 | OXETANE-CONTAINING COMPOUNDS AND COMPOSITIONS THEREOF | HENKEL AG & CO. KGAA (DE) | 2013-04-04 | — | — | WO | disclosed |