Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25207144 | 0.81 | GAA (0.56) | F10PTGS2USP2KMT2A | |
| SCHEMBL1675835 | 0.77 | F10 (0.50) | F10PTGS2USP2 | |
| SCHEMBL19086546 | 0.77 | F10 (0.54) | F10PTGS2KMT2AKDM1A | |
| SCHEMBL17552096 | 0.76 | NPC1 (0.69) | NPC1RAB9AHTTKMT2AMGLL | |
| SCHEMBL28408781 | 0.76 | F10 (0.50) | F10PTGS2 | |
| SCHEMBL2178470 | 0.76 | F10 (0.73) | F10PTGS2NPC1RAB9APOLB | |
| SCHEMBL10132893 | 0.73 | ABL1 (0.55) | NPC1RAB9AUSP2HTTPOLB | |
| SCHEMBL198132 | 0.73 | PTGS2 (0.57) | F10PTGS2NPC1RAB9AMEN1 | |
| SCHEMBL5108159 | 0.73 | NPC1 (0.69) | NPC1RAB9AHTTKMT2AMGLL | |
| SCHEMBL27627184 | 0.73 | KMT2A (0.48) | F10PTGS2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013046211-A1 | PROCESSES FOR THE PREPARATION OF 5-CHLORO-N-({(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL) PHENYL]-1,3-OXAZOLIDIN-5-YL}METHYL)-2-THIOPHENE-CARBOXAMIDE AND INTERMEDIATES THEREOF | SYMED LABS LIMITED (IN) | 2013-04-04 | — | — | WO | disclosed |