SCHEMBL14830807

SCHEMBL14830807

CC1CC=C[N+]1([O-])C(=O)OCc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
HTR2C P28335 1/20 0.42
TSHR P16473 2/20 0.40
MAPK1 P28482 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A3 Q01959 1/20 0.40
KMT2A Q03164 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
GAA P10253 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1972879 0.72 ALDH1A1 (0.49) ALDH1A1TSHRMAPK1L3MBTL1SLC6A2
SCHEMBL9785319 0.69 ALDH1A1 (0.49) ALDH1A1TSHRMAPK1L3MBTL1SLC6A2
SCHEMBL4167580 0.69 ALDH1A1 (0.49) ALDH1A1TSHRMAPK1L3MBTL1SLC6A2
SCHEMBL14189982 0.69 CPB1 (0.54) ALDH1A1TSHRGAANPC1RAB9A
SCHEMBL7612079 0.68 TSHR (0.43) ALDH1A1HTR2CTSHRMAPK1L3MBTL1
SCHEMBL1128419 0.68 ALDH1A1 (0.47) ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3
SCHEMBL3295119 0.68 CYP2C19 (0.45) ALDH1A1HTR2CTSHRMAPK1L3MBTL1
SCHEMBL2159645 0.65 ALDH1A1 (0.52) ALDH1A1TSHRMAPK1L3MBTL1SLC6A2
SCHEMBL31321938 0.65 CA1 (0.62) ALDH1A1TSHRMAPK1L3MBTL1SLC6A2
SCHEMBL472117 0.65 CA1 (0.62) ALDH1A1TSHRMAPK1L3MBTL1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013045429-A1 EPR METHOD FOR FREE RADICALS DETECTION USING AT LEAST TWO DIFFERENT SPIN TRAPPING COMPOUNDS Université Catholique de Louvain (BE) 2013-04-04 WO disclosed