Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29617936 | 0.83 | CDK9 (0.46) | TLR8ALDH1A1MAPTHPGDMAPK1 | |
| SCHEMBL1022300 | 0.74 | TLR8 (0.69) | TLR8TSHRSMN1; SMN2TP53LMNA | |
| SCHEMBL8123776 | 0.72 | PRMT5 (0.49) | TLR8ALDH1A1MAPTMAPK1TSHR | |
| Trifluoromethanesulfonic Acid SCHEMBL28491100 | 0.69 | TSHR (0.63) | TLR8ALDH1A1MAPK1TSHRSMN1; SMN2 | |
| SCHEMBL9274775 | 0.69 | TLR8 (0.70) | TLR8ALDH1A1MAPTSMN1; SMN2TP53 | |
| SCHEMBL20242949 | 0.69 | TLR8 (0.70) | TLR8ALDH1A1MAPTSMN1; SMN2TP53 | |
| SCHEMBL2943250 | 0.69 | TLR8 (0.70) | TLR8ALDH1A1MAPTSMN1; SMN2TP53 | |
| SCHEMBL17053182 | 0.69 | TLR8 (0.70) | TLR8ALDH1A1MAPTSMN1; SMN2TP53 | |
| SCHEMBL31066882 | 0.69 | TLR8 (0.70) | TLR8ALDH1A1MAPTSMN1; SMN2TP53 | |
| SCHEMBL31066875 | 0.69 | TLR8 (0.70) | TLR8ALDH1A1MAPTSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2978749-A1 | OPTIONALLY PROTECTED IRIDOID-DERIVED COMPOUNDS, COMPOSITION INCLUDING SAME, USE AS A DYE FOR KERATIN FIBRES AND DEVICES | L'Oréal (FR) | 2016-02-03 | — | — | EP | disclosed |
| WO-2014155016-A1 | OPTIONALLY PROTECTED IRIDOID-DERIVED COMPOUNDS, COMPOSITION INCLUDING SAME, USE AS A DYE FOR KERATIN FIBRES AND DEVICES | L'OREAL (FR) | 2014-10-02 | — | — | WO | disclosed |
| WO-2013045702-A2 | DYE COMPOSITION COMPRISING A NON-GLYCOSYL IRIDOID COMPOUND AND A SPECIFIC NUCLEOPHILE OR AN AMINO OR THIO POLYMER, DYEING PROCESS, AND DEVICE THEREFOR | L'OREAL (FR) | 2013-04-04 | — | — | WO | disclosed |
| WO-2013045701-A2 | DYEING PROCESS USING A COMPOSITION COMPRISING A GLYCOSYL IRIDOID COMPOUND AND A NUCLEOPHILE OR AN AMINO OR THIO POLYMER, COMPOSITION AND DEVICES THEREFOR | L'OREAL (FR) | 2013-04-04 | — | — | WO | disclosed |
| WO-2013045701-A2 | DYEING PROCESS USING A COMPOSITION COMPRISING A GLYCOSYL IRIDOID COMPOUND AND A NUCLEOPHILE OR AN AMINO OR THIO POLYMER, COMPOSITION AND DEVICES THEREFOR | L'OREAL (FR) | 2013-04-04 | — | — | WO | disclosed |
| WO-2013045702-A2 | DYE COMPOSITION COMPRISING A NON-GLYCOSYL IRIDOID COMPOUND AND A SPECIFIC NUCLEOPHILE OR AN AMINO OR THIO POLYMER, DYEING PROCESS, AND DEVICE THEREFOR | L'OREAL (FR) | 2013-04-04 | — | — | WO | disclosed |