Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 5/20 | 0.51 |
| ▸ | APP | P05067 | 5/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22245904 | 0.84 | F2RL3 (0.53) | F2RL3APPPTPN1ALDH1A1HPGD | |
| SCHEMBL14838339 | 0.80 | F2RL3 (0.45) | F2RL3APPPTPN1ALDH1A1HPGD | |
| SCHEMBL22245716 | 0.78 | PTPN1 (0.43) | F2RL3APPPTPN1ALDH1A1HPGD | |
| SCHEMBL29873464 | 0.76 | APP (0.64) | APPPTPN1ALDH1A1HPGDKDM4E | |
| SCHEMBL6748778 | 0.76 | APP (0.64) | APPPTPN1ALDH1A1HPGDKDM4E | |
| SCHEMBL12277898 | 0.76 | QPCT (0.44) | F2RL3APPALDH1A1HSD17B10MAOB | |
| SCHEMBL12277953 | 0.76 | QPCT (0.44) | F2RL3APPALDH1A1HSD17B10MAOB | |
| SCHEMBL7117562 | 0.75 | MAOB (0.66) | APPPTPN1ALDH1A1HPGDKDM4E | |
| SCHEMBL23395557 | 0.74 | PTPN1 (0.52) | F2RL3APPPTPN1ALDH1A1HPGD | |
| SCHEMBL10899813 | 0.74 | APP (0.57) | F2RL3APPPTPN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108690045-B | Diarylethene compounds and uses thereof | 首诺加拿大公司 | 2022-08-30 | — | — | CN | disclosed |
| US-11124524-B2 | Diarylethene compounds and uses thereof | SOLUTIA CANADA INC. (US) | 2021-09-21 | — | — | US | disclosed |
| US-11124524-B2 | Diarylethene compounds and uses thereof | SOLUTIA CANADA INC. (US) | 2021-09-21 | — | — | US | disclosed |
| US-10556912-B2 | Diarylethene compounds and uses thereof | SWITCH MATERIALS, INC. (CA) | 2020-02-11 | — | — | US | disclosed |
| US-10556912-B2 | Diarylethene compounds and uses thereof | SWITCH MATERIALS, INC. (CA) | 2020-02-11 | — | — | US | disclosed |
| US-20190256526-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2019-08-22 | — | — | US | disclosed |
| US-20190256526-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2019-08-22 | — | — | US | disclosed |
| US-20180339995-A1 | PHOTOCHROMIC AND ELECTROCHROMIC DIARYLCYCLOPENTENE DERIVATIVES AS OPTICAL FILTERS | SWITCH MATERIALS, INC. (CA) | 2018-11-29 | — | — | US | disclosed |
| EP-3385354-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | Switch Materials, Inc. (CA) | 2018-10-10 | — | — | EP | disclosed |
| US-10072023-B2 | Diarylethene compounds and uses thereof | SWITCH MATERIALS, INC. (CA) | 2018-09-11 | — | — | US | disclosed |
| US-20160083398-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2016-03-24 | — | — | US | disclosed |
| US-9227986-B2 | Diarylethene compounds and uses thereof | SWITCH MATERIALS, INC. (CA) | 2016-01-05 | — | — | US | disclosed |
| US-9227986-B2 | Diarylethene compounds and uses thereof | SWITCH MATERIALS, INC. (CA) | 2016-01-05 | — | — | US | disclosed |
| US-9227986-B2 | Diarylethene compounds and uses thereof | SWITCH MATERIALS, INC. (CA) | 2016-01-05 | — | — | US | disclosed |
| US-20140256936-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2014-09-11 | — | — | US | disclosed |
| US-20140256936-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2014-09-11 | — | — | US | disclosed |
| US-20140256936-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2014-09-11 | — | — | US | disclosed |
| EP-2760969-A1 | PHOTOCHROMIC AND ELECTROCHROMIC DIARYLCYCLOPENTENE DERIVATIVES AS OPTICAL FILTERS | Switch Materials, Inc. (CA) | 2014-08-06 | — | — | EP | disclosed |
| WO-2013044371-A1 | PHOTOCHROMIC AND ELECTROCHROMIC DIARYLCYCLOPENTENE DERIVATIVES AS OPTICAL FILTERS | SWITCH MATERIALS, INC. (CA) | 2013-04-04 | — | — | WO | disclosed |
| WO-2013044371-A1 | PHOTOCHROMIC AND ELECTROCHROMIC DIARYLCYCLOPENTENE DERIVATIVES AS OPTICAL FILTERS | SWITCH MATERIALS, INC. (CA) | 2013-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190256526-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | KCNH2, KCNH3, SCN2B | F2RL3 3370/4885APP 3371/4885PTPN1 2661/4885 |
| US-10556912-B2 | Diarylethene compounds and uses thereof | KCNH2, KCNH3, SCN2B | F2RL3 3370/4885APP 3371/4885PTPN1 2661/4885 |
| US-11124524-B2 | Diarylethene compounds and uses thereof | KCNH2, KCNH3, SCN2B | F2RL3 3370/4885APP 3371/4885PTPN1 2661/4885 |
| US-20180339995-A1 | PHOTOCHROMIC AND ELECTROCHROMIC DIARYLCYCLOPENTENE DERIVATIVES AS OPTICAL FILTERS | HCN2, KCNH2, KCNH3 | F2RL3 2473/4885APP 3543/4885PTPN1 3473/4885 |
| US-20140256936-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | KCNH2, KCNH3, SCN2B | F2RL3 3370/4885APP 3371/4885PTPN1 2661/4885 |
| US-20160083398-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | KCNH2, KCNH3, SCN2B | F2RL3 3370/4885APP 3371/4885PTPN1 2661/4885 |
| US-10072023-B2 | Diarylethene compounds and uses thereof | KCNH2, KCNH3, SCN2B | F2RL3 3370/4885APP 3371/4885PTPN1 2661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.