Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP1A1 | P05023 | 12/20 | 0.66 |
| ▸ | ATP1B1 | P05026 | 12/20 | 0.66 |
| ▸ | ATP1A3 | P13637 | 12/20 | 0.66 |
| ▸ | ATP1B2 | P14415 | 12/20 | 0.66 |
| ▸ | ATP1A2 | P50993 | 12/20 | 0.66 |
| ▸ | ATP1B3 | P54709 | 12/20 | 0.66 |
| ▸ | FXYD2 | P54710 | 12/20 | 0.66 |
| ▸ | ATP1A4 | Q13733 | 12/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.66 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.66 |
| ▸ | AR | P10275 | 1/20 | 0.66 |
| ▸ | ZFP91 | Q96JP5 | 1/20 | 0.66 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.59 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1483274 | 0.94 | ATP1A1 (0.69) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL2257591 | 0.90 | ATP1A1 (0.62) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL2228134 | 0.90 | ATP1A1 (0.62) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL18411185 | 0.90 | ATP1A1 (0.62) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL1484109 | 0.87 | ATP1A1 (0.74) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL31596253 | 0.87 | ATP1A1 (0.74) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL22607805 | 0.86 | ATP1A1 (0.73) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL12360806 | 0.85 | ATP1A1 (0.65) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL20786726 | 0.85 | ATP1A1 (0.71) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL10103814 | 0.85 | ATP1A1 (0.71) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110076278-A1 | Modulators of Hypoxia Inducible Factor-1 and Related Uses for the Treatment of Ocular Disorders | BIONAUT PHARMACEUTICALS INC | 2011-03-31 | — | — | US | claimed |
| EP-1928470-A2 | MODULATORS OF HYPOXIA INDUCIBLE FACTOR-1 AND RELATED USES FOR THE TREATMENT OF OCULAR DISORDERS | Bionaut Pharmaceuticals (US) | 2008-06-11 | — | — | EP | claimed |
| WO-2007016656-A2 | MODULATORS OF HYPOXIA INDUCIBLE FACTOR-1 AND RELATED USES FOR THE TREATMENT OF OCULAR DISORDERS | BTG INTERNATIONAL LIMITED (GB) | 2007-02-08 | — | — | WO | claimed |
| US-20110076278-A1 | Modulators of Hypoxia Inducible Factor-1 and Related Uses for the Treatment of Ocular Disorders | BIONAUT PHARMACEUTICALS INC | 2011-03-31 | — | — | US | disclosed |
| EP-1928470-A2 | MODULATORS OF HYPOXIA INDUCIBLE FACTOR-1 AND RELATED USES FOR THE TREATMENT OF OCULAR DISORDERS | Bionaut Pharmaceuticals (US) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007016656-A2 | MODULATORS OF HYPOXIA INDUCIBLE FACTOR-1 AND RELATED USES FOR THE TREATMENT OF OCULAR DISORDERS | BTG INTERNATIONAL LIMITED (GB) | 2007-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110076278-A1 | Modulators of Hypoxia Inducible Factor-1 and Related Uses for the Treatment of Ocular Disorders | HIF1A, HIF1AN, HYOU1 | ATP1A1 307/4885ATP1B1 102/4885ATP1A3 312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.