Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP1A1 | P05023 | 6/20 | 0.58 |
| ▸ | ATP1B1 | P05026 | 6/20 | 0.58 |
| ▸ | ATP1A3 | P13637 | 6/20 | 0.58 |
| ▸ | ATP1B2 | P14415 | 6/20 | 0.58 |
| ▸ | ATP1A2 | P50993 | 6/20 | 0.58 |
| ▸ | ATP1B3 | P54709 | 6/20 | 0.58 |
| ▸ | FXYD2 | P54710 | 6/20 | 0.58 |
| ▸ | ATP1A4 | Q13733 | 6/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.58 |
| ▸ | AR | P10275 | 1/20 | 0.58 |
| ▸ | ZFP91 | Q96JP5 | 1/20 | 0.58 |
| ▸ | STAT3 | P40763 | 2/20 | 0.49 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5082699 | 0.86 | ATP1A1 (0.75) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL1483302 | 0.86 | ATP1A1 (0.75) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL1483855 | 0.78 | ATP1A1 (0.62) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| Bufarenogin SCHEMBL21578316 | 0.76 | ATP1A1 (0.67) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| Bufarenogin SCHEMBL21578186 | 0.76 | ATP1A1 (0.67) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL5080351 | 0.74 | ATP1A1 (0.73) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL5079321 | 0.74 | ATP1A1 (0.62) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| Bufalin SCHEMBL23382204 | 0.74 | ATP1A1 (1.00) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| Bufalin SCHEMBL21129737 | 0.74 | ATP1A1 (1.00) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| Bufalin SCHEMBL21083171 | 0.74 | ATP1A1 (1.00) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110076278-A1 | Modulators of Hypoxia Inducible Factor-1 and Related Uses for the Treatment of Ocular Disorders | BIONAUT PHARMACEUTICALS INC | 2011-03-31 | — | — | US | claimed |
| US-20110076278-A1 | Modulators of Hypoxia Inducible Factor-1 and Related Uses for the Treatment of Ocular Disorders | BIONAUT PHARMACEUTICALS INC | 2011-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110076278-A1 | Modulators of Hypoxia Inducible Factor-1 and Related Uses for the Treatment of Ocular Disorders | HIF1A, HIF1AN, HYOU1 | ATP1A1 307/4885ATP1B1 102/4885ATP1A3 312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.