Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 4/20 | 0.48 |
| ▸ | CCR3 | P51677 | 2/20 | 0.48 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14834286 | 1.00 | DRD2 (0.52) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL14834122 | 0.89 | MAPT (0.48) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL14834125 | 0.89 | MAPT (0.48) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL14834017 | 0.85 | MGLL (0.52) | MGLLMAOAMAOBSMN1; SMN2 | |
| SCHEMBL15050814 | 0.85 | MGLL (0.52) | MGLLMAOAMAOBSMN1; SMN2 | |
| SCHEMBL14834457 | 0.81 | BCHE (0.48) | MGLLABHD6MAOAMAOBSMN1; SMN2 | |
| SCHEMBL15050749 | 0.81 | BCHE (0.48) | MGLLABHD6MAOAMAOBSMN1; SMN2 | |
| SCHEMBL27900180 | 0.80 | DRD2 (0.64) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL27900177 | 0.80 | DRD2 (0.64) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL14834256 | 0.79 | EPHX2 (0.57) | DRD2MGLLRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2576507-B1 | HEXAFLUOROISOPROPYL CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI SA (FR) | 2017-04-05 | — | — | EP | disclosed |
| EP-2576507-A1 | HEXAFLUOROISOPROPYL CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2013-04-10 | — | — | EP | disclosed |
| WO-2011151808-A1 | HEXAFLUOROISOPROPYL CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2011-12-08 | — | — | WO | disclosed |