SCHEMBL1483571

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1483267	0.90	EGFR (0.36)	EGFRGRIN2CKDM4EMEN1ALDH1A1
	SCHEMBL1482972	0.80	EGFR (0.39)	EGFRGRIN2CKDM4EMEN1ALDH1A1
	SCHEMBL1482861	0.80	PDE2A (0.36)	ALDH1A1PDE2A
	SCHEMBL1483351	0.78	EGFR (0.38)	EGFRGRIN2CKDM4EMEN1ALDH1A1
	SCHEMBL1484311	0.76	EGFR (0.40)	EGFRGRIN2CKDM4EMEN1ALDH1A1
	SCHEMBL1484308	0.74	EGFR (0.36)	EGFRKDM4EMEN1ALDH1A1KMT2A
	SCHEMBL27725905	0.73	EGFR (0.38)	EGFRGRIN2CKDM4ENPC1MAPT
	SCHEMBL27746910	0.72	EGFR (0.35)	EGFRKDM4ENPC1MAPTNFKB1
	SCHEMBL1483195	0.70	PRKCZ (0.35)	KDM4EMEN1ALDH1A1KMT2ANPC1
	Dimethyl Sulfoxide SCHEMBL5739758	0.70	EGFR (0.33)	EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.