Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.78 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.72 |
| ▸ | MAOA | P21397 | 2/20 | 0.69 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.60 |
| ▸ | CTSL | P07711 | 1/20 | 0.60 |
| ▸ | CTSB | P07858 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | DPP4 | P27487 | 3/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | P4HB | P07237 | 1/20 | 0.59 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | F3 | P13726 | 1/20 | 0.59 |
| ▸ | XDH | P47989 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14837108 | 0.94 | ABCG2 (0.78) | ABCG2CHRNA7MAOADPP4MAPT | |
| SCHEMBL5606932 | 0.94 | ABCG2 (0.78) | ABCG2CHRNA7MAOADPP4MAPT | |
| SCHEMBL5606285 | 0.91 | ABCG2 (0.72) | ABCG2CHRNA7MAOADPP4MAPT | |
| SCHEMBL28400854 | 0.90 | ABCG2 (0.72) | ABCG2CHRNA7MAOANFKB1NFKB2 | |
| SCHEMBL14837404 | 0.90 | ABCG2 (0.72) | ABCG2CHRNA7MAOANFKB1NFKB2 | |
| SCHEMBL28695326 | 0.90 | CTSL (0.66) | ABCG2CHRNA7MAOACAPN1CTSL | |
| SCHEMBL28695325 | 0.90 | CTSL (0.66) | ABCG2CHRNA7MAOACAPN1CTSL | |
| SCHEMBL4160326 | 0.89 | ABCG2 (0.68) | ABCG2CHRNA7MAOATDP1DPP4 | |
| SCHEMBL15155210 | 0.85 | ABCG2 (0.94) | ABCG2MAOAMAPTRAB9AMEN1 | |
| SCHEMBL15155219 | 0.85 | ABCG2 (0.94) | ABCG2MAOAMAPTRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2578222-A1 | Plant extract composition | Lanwehr, Christoph Alexander Bernhard (DE) | 2013-04-10 | — | — | EP | claimed |
| EP-2578222-A1 | Plant extract composition | Lanwehr, Christoph Alexander Bernhard (DE) | 2013-04-10 | — | — | EP | disclosed |